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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Genomic testing for deafness and its implications

Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...

Decreased sound tolerance in autism: understanding and distinguishing between hyperacusis, misophonia, and phonophobia

Decreased sound tolerance (DST) affects a significant proportion of autistic people throughout their lifetime and, as Zachary J Williams explains, it is important that clinicians are aware of the three distinct subtypes of DST when making a diagnosis. Autism spectrum...

Thyroid nodules – time for a rational imaging approach

“The more you know, the harder it is to take decisive action. Once you become informed, you start seeing complexities and shades of gray. You realize that nothing is as clear as it first appears. Ultimately, knowledge is paralyzing.” Calvin,...

Patient and public involvement in research

One step further from involving patients in setting research priorities is to involve them in the planning and recruitment stages of the subsequent trials and studies. Here, Carl Philpott and Aneeka Degun explain the concept of Patient and Public Involvement...

Tonsillectomy in adolescents

Tonsillectomy is one of the most common operations performed across the developed world. Salil Sood and Ray Clarke discuss the special considerations that apply when performing this procedure on adolescent patients. Tonsillitis in teenagers can be exceptionally painful and disruptive....

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...

From surgeon to scholar: the remarkable life of Philip Stell

Professor Philip Stell was an extraordinary man: following an astonishingly illustrious career in ENT, he excelled as a medieval historian. With the Philip Stell Prize due to be awarded in May, his friend Pat Bradley looks back at his remarkable...

Nasal sidewall reconstruction

Expert reconstruction of nasal sidewall defects requires careful selection of techniques across nasal layers, balancing aesthetics, structural support and patient needs. When reconstructing a nasal skin defect, a variety of factors should be taken into account in order to achieve...