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Active surveillance for papillary thyroid cancers – what is the risk of progression?
Papillary thyroid cancers (PTCs) are generally considered to be indolent malignancies with favourable outcomes. Active surveillance (AS) has consequently been trialled as a management option for small PTCs with no evidence of regional lymph node involvement, especially papillary thyroid microcarcinomas...
Nasal nitric oxide – an inflammatory marker in paediatric allergic rhinitis?
Nasal nitric oxide (nNO) is mainly produced in the paranasal sinus mucosa and was shown in some studies to have increased expression in allergic rhinitis (AR). Although it represents a potential non-invasive tool for AR measurement, there remains no consensus...Supporting patients with chronic dizziness and investing in vestibular research
The Ménière’s Society is the UK’s leading vestibular charity. Their team is available to help patients access reliable information, source a vestibular specialist or talk to someone who understands what they’re going through.
Intra orbital treatment to save the eye!
Invasive fungal sinusitis can be a devastating condition, and accepted management is surgical debridement of infected tissue, systemic antifungal treatment and reversal of immunosuppression. Orbital involvement is common, affecting up to 75% of cases, and in advanced disease orbital exenteration...
Hear me out – tiny steroid implants for fighting meningitis-induced deafness
Sensorineural hearing loss is the most common neurological complication of pneumococcal meningitis. Bacterial infiltration into the inner ear triggers inflammation, leading to cochlear fibrosis and sclerosis – damage that, in over a third of cases, affects both ears. Current Infectious...COOL therapy for cisplatin-induced hearing loss
Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies
Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...
The right to choose: the how-to of practicable supports
Providing all practicable supports to enable a person to participate in decision-making is one of the five key principles of the English and Welsh Mental Capacity Act 2005. This article (set in the Canadian legal framework, which has many similarities...
Advancing the tongue in OSA surgery
This article further delineates the options for hypopharyngeal OSA and describes the technique of genioglossus advancement to improve the tension in the tongue base. The authors take the reader through the relevant anatomy appropriate to the procedure and describe the...Tone deafness and perfect pitch
If you think you are tone deaf, do not despair. Singing tuition should help but it is probably too late to hope to develop perfect pitch. Consultant otolaryngologist and keen musician, Chris Aldren, discusses the complex and fascinating subject of...What does functional neuroimaging tell us about tinnitus?
One of the most common causes of tinnitus is noise exposure, be that either cumulative day-to-day exposure over a lifetime or experience of acute noise trauma such as a loud concert or shooting incident. Observational data indicate that up to...
