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New aminoglycosides with reduced ototoxicity risk

Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...

Persistent dysphonia due to cricothyroid muscle dystonia – should we be requesting laryngeal EMGs for non-resolving ‘functional’ dysphonia?

This article is an interesting report of a case of persistent voice problems affecting a 43-year-old physician that significantly compromised her ability to converse and communicate at work. Specifically, she had a fluctuating voice quality that would ‘choke off’, combined...

Clinical value of 3 T magnetic resonance imaging after intratympanic gadolinium injection in cases of delayed endolymphatic hydrops

Recurrent vertigo can continue after severe unilateral or bilateral hearing loss. This is a condition similar to Ménière’s disease, the diagnosis of which can be difficult. In this study intratympanic injection of gadolinium-diethylenetriamine penta-acetic acid dimeglumine was done in 25...

Why and what should hearing care professionals know about cognitive impairment and dementia

Good reasons to care about cognitive impairment and dementia in audiology If asking people what they fear most when getting to old age, it is cognitive decline that is named most often. This comes with the expectation of limitations in...

In conversation with Dr Narveshwar Sinha

‘Only if you hear, you speak’ – early diagnosis of deafness On the occasion of World Hearing Day, Vikas Malik interviewed Narveshwar Sinha, Chairman of IDEAL Charity, a UK-based charity working for the hearing impaired in less developed countries for...

The use of repositioning chairs in the diagnosis and treatment of BPPV

The authors performed a systematic review assessing the utilisation of multi-axial repositioning chairs, such as the TRV chair and the Epley Omniax Rotator, in the diagnosis and treatment of BPPV. They reviewed nine studies, of which four were prospective studies....

Dysphagia in people with HPV-related oropharyngeal cancer

Human papilloma virus (HPV) associated oropharyngeal cancers are becoming much more prevalent and, in some geographic areas, have overtaken tobacco as the leading cause of oropharyngeal cancer. HPV-associated cancers are also reported to have better prognosis in general, and research...

Can tympanometry be used to diagnose Ménière’s disease?

The authors proposed multifrequency tympanometry (MFT) as an in-office test which may be able to diagnose Ménière’s disease (MD) that is quicker and more cost-effective than other methods. MFT measures the acoustic admittance of the middle ear and external ear...

Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...

Staying safe during endoscopic ear surgery

There is growing interest in using rigid endoscopes rather than traditional operative microscopes to perform transcanal middle ear surgery. Rigid endoscopy provides a high resolution, wide-angle view of the tympanic cavity through minimally invasive surgical portals. In this article, Elliott...

Update on the development of an implantable vestibular prosthesis

Cochlear implants have revolutionised the management of profound hearing loss. Might vestibular implants be the future for the treatment of bilateral vestibular failure? James Johnston and Neil Donnelly explore. The vestibular system is highly complex, integrating visual, labyrinthine and proprioceptive...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...