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eNOS and OME

The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...

3D is the future?

This is an interesting take on yet another way to incorporate modern technology into medical practice, and the novel use of a 3D printer to create a custom-made prosthesis for large and irregular nasal septal perforations. These prostheses have the...

BAHAs in single-sided deafness doesn’t improve sound localisation

This systematic review from South Korea nicely summarises what we know about SSD (single-sided deafness) and hearing rehabilitation with BAHAs (Bone Anchored Hearing Aids). SSD was defined as a PTA greater than 90 dB and a normal hearing opposite ear...

Risk of malignancy in non-diagnostic thyroid FNACs

Thyroid nodules are present in between 21-68% of the general population. The evaluation of these nodules to exclude thyroid carcinoma includes fine-needle aspiration cytology (FNAC) and a non-diagnostic cytology result occurs between 8-20% of the time. This retrospective cohort study...

Predicting speech recognition in adults with cochlear implants

This was a combined prospective and retrospective study from Belgium that looked at factors influencing speech recognition scores in quiet conditions (retrospectively) and speech reception threshold levels (SRT) in fixed noise conditions (prospectively) after cochlear implantation in postlingually deaf adults....

Voice impairment following spinal cord injury

Patients with cervical spinal cord injury face several clinical problems. One of the problems is voice impairment secondary to poor respiratory support. Their syllables per breath, vocal intensity and vocal quality are impaired. This paper studied the impact of the...

Blood type and epistaxis

In this Turkish study, the authors attempted to determine if there was an association between ABO blood type and epistaxis. They looked at 359 epistaxis admissions at the same hospital over a three-year period. Only patients with idiopathic epistaxis were...

Surgery of vestibular schwannomas with peritumoral oedema

This is an interesting retrospective study evaluating peritumoral oedema on magnetic resonance images and correlating it with the intra-operative tumour characteristics and outcome. The study results found that vestibular schwannomas with peritumoral oedema were associated with greater incidence of hypervascularity...

Fluorescein use during parotidectomy

The authors of this study retrospectively reviewed the surgical charts of seven patients who underwent parotidectomy for tumour resection. In all these patients, Fluorescein sodium was used to enhance the contrast between parotid tumour tissue and the facial nerve. Using...

Sleep before and after nasal polyposis surgery

This prospective French study looked at the change in nasal symptoms related to sleep, in a questionnaire before and after nasal polyposis surgery. Sixty-three patients who underwent endoscopic sinus surgery completed the DyNaChron questionnaire before, at six weeks and at...

Post-thyroidectomy vocal cord palsy: are there long-term sequelae?

This is a well written paper utilising the Hospital Episode Statistics dataset for all thyroidectomies performed in England between 2004 and 2012. The study had a very impressive 43,515 participants and only included young, fit patients undergoing thyroidectomy once for...

Obstructive sleep apnoea: Does maxillomandibular advancement work?

This is a paper from the Netherlands reviewing 62 patients who underwent maxillomandibular advancement for moderate to severe obstructive sleep apnoea. The authors observed a 71% success rate with mean apnoea hypopnea index (AHI) reduction of 69%. There was no...