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Genetics of IP-III
The authors provide a literature review of the genetic basis and clinical features of incomplete partition (IP)-type III. The condition is seen typically in males and is due to mutation in the POU class 3 homeobox 4 (POU3F4) gene which...What do animal models tell us about tinnitus and hyperacusis?
Do animals have tinnitus? The obvious question to ask is: do animals have tinnitus? It is known that tinnitus is a conscious percept and as such affected by attention and not audible during sleep. For it to be demonstrated that...Human immunodeficiency virus and hearing impairment
With an estimated 36.7 million individuals living with HIV / AIDS and literature reporting that these conditions contribute to hearing loss, it is surprising that more focus and resources are not employed to tackle this major hearing health concern. Yolandé...In conversation with Trevor McGill
After more than four decades of paediatric clinical practice, Trevor McGill shares his wealth of experience and knowledge with Pat Bradley. Trevor, as a national and internationally acknowledged Paediatric Oto-Rhino-Laryngologist, Head and Neck Surgeon, to what do you owe this...
Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...
Otolith dysfunction in congenitally deaf adults
This paper helps to further define the profile of ocular and cervical vestibular-evoked myogenic potentials (o and c VEMPs) in patients with congenital profound sensorineural hearing loss (PSHL). It highlights the prevalence of otolith (saccular and utricular) dysfunction that exists...
Spasmodic dysphonia – is greater awareness needed?
Spasmodic dysphonia (SD) is a focal dystonia of the laryngeal musculature. Previously considered to be a rare disorder, it has more recently been suggested that SD is in fact not rare but is frequently misdiagnosed or undiagnosed. This paper would...
