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Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?

Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....

Surgical management of refractory osteoradionecrosis

This is a French single-centre, 10-year experience of 55 surgical resection and reconstruction procedures. They claim an overall effectiveness rate of 92.3%. A total of 36 segmental and 19 marginal mandibulectomies were performed. A variety of free flaps were used,...

Ultrasound-guided core biopsy of neck lumps as first-line investigative modality supersedes fine needle aspiration cytology in the diagnosis of neck lumps

Ultrasound-guided fine needle aspiration cytology (USFNAC) when applied as initial investigation often proves non-diagnostic, the incidence being as high as 50% in a recent audit. In this study, the authors applied ultrasound-guided core biopsy (USCB) to neck lumps over 1cm...

Clinical pathological features associated with malignant change in oral leukoplakias

This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...

Sinonasal inverting papilloma and HPV - a meta-analysis of recurrent tumours

Sinonasal inverting papilloma (SNIP) is a common benign tumour of the sinuses. Difficulty lies in the association with metachronous or synchronous SCC of the sinus and also in the complete removal of the lesions due to their anatomical location. An...

Malignant transformation of leukoplakia in previous cancer patients

This is a retrospective study from Taiwan assessing risk factors in developing oral squamous cell carcinoma from surgically excised oral leukoplakia in patients with a previous oral cancer, the underlying thought being that patients with an oral carcinoma have a...

Conductive hearing loss – when and why to scan

Ossicular fixation or discontinuity can occur at any point along the ossicular chain and is estimated to cause conductive hearing loss (CHL) in approximately 55% of patients. Computed tomography (CT) imaging of the temporal bone identifies bony pathologies that contribute...

Outcomes and progress of a well-designed one-stop head and neck lump clinic

With increasing caseload of head and neck cancer and the fact, as reported by UK Government in October 2024, that over half of these cases are diagnosed at an advanced stage, the need for early diagnosis and prompt management is...

Comprehensive Management of Skull Base Tumors – Second Edition

This is the second edition of a multi-author textbook first published over a decade ago. Most of the chapter authors are North American, as are the editors themselves. There is also a smattering of well-known contributors from the rest of...