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The changing spectrum of cancer of the oropharynx: dilemmas and future directions
The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....
Antiseptics to combat otorrhea in the era of antibiotic resistance
This nice scientific paper pits various antiseptic solutions against each other to determine which has the most bactericidal properties. Five different antiseptics were applied to MRSA and quinolone-resistant pseudomonas species, which are both difficult to treat with conventional ototoxic medications....
Botox application for drooling shrinks salivary glands
The large majority of sialorrhoea (drooling) in paediatric patients is managed conservatively. However in severe cases, often where there is associated developmental delay or a motor disorder, medical and surgical techniques can be used to decrease salivary flow. Botulinum toxin...
Interleukins, cilia and polyps
Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...
What do we put in our nasal douches? Anything?
The rise of the popularity of saline nasal douches, with several commercial preparations available, may be a rediscovery of an age-old tradition, but it has been shown to benefit patients. The question then arises as to whether this can be...
Is there evidence to support early discharge of patients with tonsillitis, quinsy and epistaxis?
The COVID-19 pandemic, with its unprecedented pressures on the NHS, demands changes in the management of common ENT emergencies. In this review article, information has been gleaned from 22 relevant articles on how this can be done. The Portsmouth tonsillitis...
