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2359 results found

Retrospective review of paediatric salivary gland tumours

As is the case with adults, primary tumours of the salivary glands in children comprise a heterogeneous collection of different histological types. This paper presents a retrospective review of primary salivary gland tumours in children treated over the course of...

Chronic rhinosinusitis – a pre-malignant condition?

Nasopharyngeal carcinoma (NPC) is a relatively uncommon diagnosis in the West but is prevalent in Southeast Asia. Several factors have been established to be associated with a higher risk of developing NPC, including salted fish consumption, smoking, alcohol, and Epstein...

3D planning of soft-to-hard tissue ratios in orthognathic surgery

This multinational systematic review examined publications over a six-year period up to December 2023, focusing on orthognathic surgery. It follows an earlier review by the same group, which had reported low validity in the use of 3D software for soft-to-hard...

Migraine medication and benign paroxysmal positional vertigo (BPPV)

BPPV is a very common form of dizziness (lifetime prevalence 2.4%) and has been noted to have an association with migraine. The cause of otoconia displacement in BPPV is often unclear. A vascular mechanism theory has been postulated in varying...

Posterior TM perforations carry greater hearing loss: practical pointers for clinic

This single-centre prospective study of 100 adults with central pars tensa perforations examined how perforation size and quadrant relate to hearing loss. Using video-otoscopy to estimate perforation area and pure tone audiometry for thresholds, the authors found hearing loss in...

The keystone island perforator flap – expanding the toolbox for aesthetic nasal reconstruction

The complexity of nasal reconstruction lies in its dual objective: restoring structural integrity while preserving subtle contours and symmetry that define facial aesthetics. This retrospective cohort study from a single centre in the United States evaluated the effectiveness of the...

Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up

This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...

Exploring the role of oral microbiota in head and neck squamous cell carcinoma

Oral microbiota, especially Fusobacterium nucleatum, may improve survival and guide personalised treatment in head and neck squamous cell carcinoma. Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with a low five-year survival rate that has shown little...

Antibiotic prophylaxis in otolaryngologic surgery. Less is better!

Jan/Feb 2020 Editor’s Choice is a review of antibiotic prophylaxis in ENT and OMF surgery. It is not the first systematic review and meta-analysis published in the last two years. If anyone else has been offered a “potentially career-altering opportunity”...

Neural plasticity and aural rehabilitation

Neural plasticity refers to an ability of the brain and central nervous system to change their structure and function or their reorganisation in response to environmental cues, experience, learning, behaviour, injury and / or diseases and treatments. Neural plasticity is...

Fifth Sense James Lind Alliance Priority Setting Partnership for smell and taste disorders

Research priorities in the past have been dominated by the quixotic curiosity of individual academics and the capricious generosity of funding organisations. There must be a better way... At Fifth Sense, research is fundamental to the work we do. Above...

Video otology tutorials: how EES changes the game

High definition endoscopic ear surgery (EES) redefines traditional middle ear anatomical perspectives. The surgeon can observe in situ anatomical relationships with angled objectives in a way that the traditional microscopic view, with step-wise removal of structures is unable to achieve....