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Hearing loss and Alport syndrome
Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...Reflections on organising the British Academic Conference in Otorhinolaryngology 2015
As the Local Host and Programme Director of BACO 2015, Andrew Swift is a pivotal person with local knowledge and contacts. He provides us with some top tips as to how to go about organising a successful conference. The ACC...A place for everything and everything in its place: the practicalities of randomised clinical trials
Will this pill cure tinnitus? Bonnie Millar describes one trial that has investigated the possibility whilst describing the path of drug trials in the UK. Background In the last quarter of 2014, a clinical trial (QUIET-1; ClinicalTrials.gov Identifier: NCT02315508) commenced...Staying safe during endoscopic ear surgery
There is growing interest in using rigid endoscopes rather than traditional operative microscopes to perform transcanal middle ear surgery. Rigid endoscopy provides a high resolution, wide-angle view of the tympanic cavity through minimally invasive surgical portals. In this article, Elliott...Giacomo Puccini’s laryngeal cancer
Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...
Early results of the Cochlear Osia (active transcutaneous bone-conduction implant) in teenagers
This funded research trial involving 14 adolescents, aged 10 to 17 years, in the Toronto Hospital for Sick Kids was carried out just prior to the new Osia implant obtaining FDA approval for use in the USA. The majority had...
