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Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy

Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...

Surgery for class III malocclusions pharyngeal airway and sleep apnoea effects

Thirty-three patients from Brazil were assessed for obstructive sleep apnoea and hypopnoea syndrome pre- and six months postoperatively. The 33 patients were made up of nine having mandibular set back surgery, six maxillary advancement and 18 bi-maxillary surgery. They identified...

Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach

This book sets itself apart from its peers by providing a unique interdisciplinary approach to skull base surgery. As the title implies, there is naturally a huge focus on endoscopic endonasal skull base surgery (between chapters 8 and 15). The...

Pharyngocutaneous fistula after total laryngectomy

Pharyngocutaneous fistula (PCF) after total laryngectomy is a serious complication post-surgery, and can lead to prolonged hospitalisation, adding delays in postoperative chemoradiotherapy. This Turkish retrospective study looked at 166 patients who underwent total laryngectomy for laryngeal cancer, although it is...

Chin up, doc! A few simple manoeuvres could make all the difference in FNE

Flexible nasendoscopy (FNE) is an ENT surgeon’s bread and butter. It is integral and often considered superior to conventional radiography in the assessment of laryngeal and pharyngeal cancers. However, it is not as simple as sticking the camera in and...

Manual of Allergy and Clinical Immunology for Otolaryngologists

As a first approach, the book impresses with the hardback cover and the glossy 442 pages. Published in March 2015, the book reflects an effort to deliver the main advances and updates of allergy and clinical immunology relevant to otolaryngology...

Paediatric vestibular dysfunction

This Malaysian study looked at the awareness amongst otorhinolaryngologists in the investigation and management of paediatric vestibular dysfunction. The authors noted that, although paediatric vestibular dysfunction is a common problem, there seems to be limited literature in assessing the proficiency...

Sarcoidosis and the nose

This retrospective case note review from Mount Sinai in New York looked at just 14 patients with sarcoidosis. Individual ENT units in the UK are likely to see relatively few of these patients, unless there is a major tertiary referral...

An advance in imaging for sinonasal tumours?

Benign sinonasal growths are incredibly common, and malignant sinonasal growths thankfully rare. We know that malignant tumours often present late, and the imaging can sometimes be misleading, so the authors here compare using diffusion weighted imaging (DWI), dynamic contrast enhanced...

Chronic rhinosinusitis – a pre-malignant condition?

Nasopharyngeal carcinoma (NPC) is a relatively uncommon diagnosis in the West but is prevalent in Southeast Asia. Several factors have been established to be associated with a higher risk of developing NPC, including salted fish consumption, smoking, alcohol, and Epstein...