You searched for "genomics"

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Clinicopathological features of follicular variant of papillary thyroid carcinoma

The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...

Recurrent ENT infections in children – is it a sign of primary immunodeficiency disease?

ENT clinicians often come across children with recurrent ear, sinus and pulmonary infections. These recurrent infections, albeit common in childhood, can represent an early sign of primary immunodeficiency diseases (PIDD). PIDD is an underdiagnosed group of genetic disorders involving absent...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Improving music perception in cochlear implant users

Can you imagine a world without music? In the words of Hans Christian Anderson, a prolific 19th-century Danish author, “Where words fail, music speaks.” This quote highlights music’s importance as a language of emotions that transcends linguistic barriers. This case...

In conversation with Dr John Woo and Mr Derek Skinner

Dr John Woo and Mr Derek Skinner have between them an absolute wealth of experience and expertise in the fields of surgical training and specialist examinations. Here, they tell us about their involvement in surgical education, and explain some of...

The MACRO Trial: defining best management of chronic rhinosinusitis

A major UK trial in The Lancet finds ESS provides greater symptom relief than long-term macrolides for adults with CRS, supporting earlier surgery and fewer antibiotics. The MACRO Programme was established in 2016 when the UK National Institute of Health...

5th Annual Inner Ear Disorders Therapeutics Summit

Coined by industry as the only meeting of its kind and uniquely positioned to share fresh ideas and assess viable approaches to your most pressing preclinical, translational, and clinical bottlenecks, the 5th Inner Ear Disorders Summit returns as a forum to benchmark learnings from past failures, reignite momentum and develop investment into the audiology therapeutic landscape.

Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Kallmann’s Syndrome

‘A rose by any other name would smell as sweet.’ (Shakespeare) Kallmann’s Syndrome (KS), or hereditary hypogonadal anosmia, is a rare genetic disorder characterised by delayed or absent puberty and anosmia. It is named after Franz Kallmann, but he was...

A patient-centred approach from the patient’s point of view

Seeking help for hearing loss is often a big step for patients. Shari Eberts, a hearing health advocate living with hearing loss, explains why, and gives us her five top tips to improve patient-centred care in such cases. Sensorineural hearing...

BAAP Annual Conference 2026

Amol Anand, Speciality Registrar in Audiovestibular Medicine, Guy’s and St Thomas NHS Hospital Trust, UK Sabarinath Vijaykumar, Speciality Registrar in Audiovestibular Medicine, Royal Derby Hospitals, UK Dr Thomas Wedell, Speciality Registrar in Audiovestibular Medicine, Guy’s and St Thomas NHS Hospital...

Development of a new negative-pressure ventilatory support device: Exovent

The pandemic has driven innovation in ways that we have not seen for many decades. Intensive care medicine and ENT have been at the forefront of these advances, and our good friends David Howard (never one to put his feet...