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1513 results found

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

Laryngeal papillomatosis

Laryngeal papillomatosis remains one of the most frustrating conditions seen by laryngologists. Sam Majumdar gives us an overview of the current science and clinical practice. Human papilloma virus is a small (> 8kb) double stranded DNA virus with approximately 200...

Laryngeal transplantation: is it a thing?

Few organs could be said to be more complex than the larynx when it comes to transplantation. Martin Birchall looks at past challenges, current issues and future prospects. I am not clear exactly why I chose to spend a life...

Trainee-led collaborative research and audit in ENT: where are we now?

In late 2015 INTEGRATE, the UK ENT Trainee Research Network, was formed. Since then, two national projects have been completed and INTEGRATE has grown into a larger, more structured organisation, with otology, head and neck and rhinology subcommittees working alongside...

Brussels, a multicultural city with varied ENT practice

Brussels has a proud history in the world of ENT. Jérome Lechien, who is on the Communications Committee for the CEORL-HNS 2019 Congress, and Daniele de Siati, a member of the international Scientific Committee, give us a history lesson and...

Head and neck cancer awareness

Head and neck cancer is one of the most preventable cancers, and awareness and screening campaigns have shown a decline in its incidence. Support for campaigns of awareness and education about these cancers is crucial from professional, societal and governmental...

Hypoglossal nerve stimulation for OSA: current experience with unilateral versus bilateral systems

Hypoglossal nerve stimulation (HNS) has emerged as an established treatment option for selected patients with obstructive sleep apnoea (OSA) who are intolerant to continuous positive airway pressure (CPAP). Over the past decade, technological developments have expanded the field from unilateral...

Salivary duct clipping for drooling

Drooling can be a challenging problem to manage in paediatric ENT. The variety of medical and surgical treatments suggests that there is no gold standard treatment. Nicola Stobbs and Ravi Thevasagayam describe an approach to ligating the salivary ducts. Drooling...

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Ultramarathons, frostbite and running with wolves

“I could just keep going when most sane people would stop”- the secret to success in head and neck surgery? In August 2015 I crossed the finish line of La Ultra - The High. A small camp of tents and...

Is Dymista® useful for paediatric allergic rhinitis?

Allergic rhinitis (AR) affects up to 14.6% of the paediatric population. Whilst a recent Cochrane review has considered the evidence for intranasal corticosteroids as `weak and unreliable’ in paediatric AR, this product is a novel formulation combining Fluticasone and Azelastine...