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An algorithm to distinguish between distant metastases and metachronous lung primary in patients with HPV-related oropharyngeal cancer

Distinguishing between distant metastases of HPV-related oropharyngeal squamous cell carcinoma (OPSCC) and metachronous primary lung squamous cell carcinoma (SCC) is important as it has implications for treatment, prognosis counselling, and registry data. Although p16 immunohistochemistry (p16 IHC) is widely accepted...

Chronic rhinosinusitis and sleep

This is an interesting article from the Chung Shan Medical University in Taiwan. One-hundred-and-thirty-nine patients were enrolled into this five-year study. They all had chronic rhinosinusitis with or without polyposis and underwent sinus surgery. The aim was to investigate a...

Does a labyrinthine fistula in cholesteatoma surgery lead to hearing loss?

Thirty-five patients with labyrinthine fistula related to cholesteatoma were studied retrospectively. All patients underwent CT scans and preoperative hearing tests 1-2 weeks prior to surgery (averaged at 0.5, 1, 2, 3, 4, 8 kHz). All 35 patients underwent mastoid surgery,...

Cochlear implanted children are more likely to have device failure if their balance function is impaired

We know that children with permanent hearing loss are more likely to have an associated balance problem. It is also thought that children with cochlear implants (CI) that fail do so because of an increased risk of falls and head...

Are upper respiratory symptoms and macroscopic changes in children always due to gastro-oesphageal reflux?

In children, symptoms such as chronic cough, wheezing, stridor, voice changes, persistent asthma and dental erosion are often presumed to be due to gastro-oesophageal reflux and empirical treatment with PPIs is offered. Usual investigations, such as a barium meal, gastroscopy...

Three years later: report on the state of well-being of patients with chronic tinnitus who underwent modified tinnitus retraining therapy

This paper reports on 130 patients with tinnitus of at least three months duration who underwent ‘Modified Tinnitus Retraining Therapy’ (MTRT). MTRT combines psychological and physical therapies with standard tinnitus retraining therapy provided as a course of multi-disciplinary treatment, as...

Cochlear implants with an absent or hypoplastic cochlear nerve?

The cornerstone of successful cochlear implantation has been the presence of a population of cochlear nerve endings which are able to mount a neural response to electrical stimulation. The authors of this paper present their experience of five children with...

Head and neck radiation and the brain

An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...

Tinnitus loudness and insomnia

Tinnitus may be very bothersome for its sufferers, in some cases leading to suicide. Therefore, it is extremely important to offer the best available treatment to people suffering from tinnitus. This study considered whether insomnia may be associated with the...

Genetic testing in congenital hearing loss

Advances in genetic testing over the last decade have reduced the cost and time such testing required and increased understanding of the genes involved in conditions like congenital hearing loss. This study from Atlanta looks at genetic testing from a...

Horizontal canal PPV: is Gufoni manoeuvre better than barbecue manoeuvre?

Benign paroxysmal positional vertigo (BPPV) is the most common kind of vertigo that we come across in our out-patient clinic. Horizontal canal BPPV (HC-BPPV) accounts for 10–30% of total BPPV. Two techniques, namely Guffoni and barbecue roll manoeuvres, are generally...

The impact of bilateral implantation on language outcomes

An American study retrospectively looked at the language outcomes of 204 children implanted either bilaterally, sequentially or unilaterally. All children received their first implant before the age of three years, and language measures were collected when the children were aged...