You searched for "Genetic"

1453 results found

Age and vocal cord carcinoma

As the population ages, the management of vocal fold carcinomas should be evaluated. In this retrospective study on 33 patients aged 75 and more, the authors compared the results of radiotherapy and endoscopic treatment for T1 and T2 glottic carcinoma....

Transoral laser microsurgery (TLM)

This review article describes the surgical technique of transoral laser microsurgery (TLM) for the piecemeal removal of tumours of the upper aerodigestive tract using carbon dioxide laser. This technique gained acceptance after Wolfgang Steiner published his paper on the treatment...

New MRI technique assesses treatment response in skull base osteomyelitis

This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...

St Blaise - patron saint of the throat

In a previous article, we looked at some interesting legends surrounding patron saints of the ear and hearing [1]. As we celebrate the Feast Day of St Blaise of Sebastia on 3 February, we hear some fascinating tales and myths...

An update on HPV and the vaccination

In recent years, the role of HPV in the development of oropharyngeal cancers has become apparent. Hannah Fox and Vin Paleri contend that while we may not always be able to cure oropharyngeal cancers, vaccination offers our best hope for...

2014: Are today’s implantable devices better than conventional solutions for patients with conductive or mixed hearing loss?

Patients with conductive or mixed hearing loss become candidates for amplification when reconstructive surgery is not viable. Three common amplification options are conventional acoustic devices, such as behind-the-ear devices (BTEs), (implantable) bone-conduction devices and active middle ear implants. The goal...

Are vascular loops at the CPA of any clinical significance?

Neurotologists have grappled with this question for many years. The aim of the study was to determine the clinical relationship of vertigo symptoms with vascular loop compression syndrome using 3D T2WI turbo spin echo high-resolution MRI. The study included 417...

MRI and the endolymphatic space

This is an interesting study which was performed to evaluate the endolymphatic space in patients with endolymphatic hydrops (EH), using MR imaging. Seven patients aged between 21–77 years; five female, two male with unilateral or bilateral symptoms of EH were...

Head and neck radiation and the brain

An increasing number of patients with head and neck squamous cell carcinoma and other lesions are treated with high dose radiotherapy. An increase in survival rates is being reported along with a younger patient demographic. The long-term effects of treatment...

Radiological diagnosis of mastoiditis in patients screened for acoustic neuroma

Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have acoustic neuroma. Various abnormalities are picked up through this investigation, one of which, not uncommonly reported, is mastoiditis. This requires referral to otolaryngology and further evaluation. In...

A cost reducing protocol for magnetic resonance imaging in patients suspected to have acoustic neuroma

Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have an acoustic neuroma. However, inappropriate referrals for imaging are not helpful, especially with the growing need to reduce costs. In this study the authors compared two audit...

Role of non-echo planar diffusion weighted magnetic resonance imaging in detection of cholesteatoma

Whilst the method of canal wall down and same-session reconstruction is emerging to be more popular, canal wall up procedures are still performed. In either, it is necessary to ensure eradication of cholesteatoma or detect its recurrence. The reliability of...