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Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Atlas of Ear Diseases

In this self-published atlas, the author has approached the external ear and middle ear pathologies on the basis of classification of diseases, emphasising the added benefits of using of an oto-endoscope in identifying the external and middle ear pathologies. The...

Aerosol research and performance

Is singing safe? This was a question asked around the world at the start of the pandemic in early 2020. Natalie Watson and Chris Orton tell us about a rapidly-convened research group that led to profound changes in UK Government...

Not the answer yet, but it may be in the future

AI is certainly a topical issue these days and radiomics refers to techniques which allow the extraction of quantitative features from medical imaging to produce large data sets for clinical problem solving. This paper looks at CT imaging of the...

Where is that sound? Not every hot tub is a jacuzzi

Evidence suggests that the incidence of sound sensitivity and general noise intolerance is increasing. Studies have suggested that the incidence of hyperacusis is between 8% and 15.2% of the adult population. There is a correlation between the prevalence of hyperacusis...

Timing of surgery in chronic rhinosinusitis: does it matter?

While many patients with chronic rhinosinusitis respond to medical treatment, some do not. The next step for these patients is surgery, but how soon should this be offered? Sooner rather than later seems to be the answer, as Claire Hopkins...

Impact of medical NGOs and a new collaborative approach: the case of Guinea with Mercy Ships

Mercy Ships (MS) is a global Christian charity that follows the 2000-year-old model of Jesus to bring hope and healing to those suffering from disability, disfigurement, and disease. This article by Professor Diallo and Drs Ugai and Conde, details a...

Smaller gauge voice prosthesis is effective in secondary trans-oesophageal puncture

Placement of voice prosthesis at the time of trachea-oesophageal puncture is well described using 20-French prostheses. There is debate about the optimal size of the prosthesis with work in the 1980s and 1990s supporting larger prostheses. The rationale was that...

A novel scale for the assessment of tracheoesophageal voice quality – the SToPS

There is currently no assessment tool in widespread use that permits a valid and reliable perceptual assessment of voice quality following laryngectomy. Such a scale is needed to investigate the functional outcomes of surgical voice restoration and rehabilitation regimes. Existing...

The impact of simulation on ENT training

Surgical training is constantly developing to improve ENT surgeons’ technical and non-technical skills. In this article, Joshua Whittaker, an ENT Registrar and ENT Simulation Fellow at University Hospitals Birmingham, describes the rise of simulation training. Simulation is the recreation of...

Developing medical devices for children: opportunities and challenges

The development of medical devices for infants and children lags significantly behind the development of devices for adults. While in the United States the Food and Drug Administration (FDA) has set up incentives for developing child age-specific pharmaceuticals, there is...

Nasal function in COVID-19 patients

This Turkish prospective study compared SNOT-22 outcomes as well as objective assessments of nasal secretion and clearance in 40 patients who tested positive on COVID-19 antigen PCR testing and 40 patients who tested negative. Sinonasal findings were assessed using a...