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Assessing the impact of e-cigarette smoke on the vocal fold

While the use of electronic-cigarettes (e-cigs) is increasing rapidly, little is known about the effects this has on the health of vocal fold. In this translational research study, authors compared the effects of e-cig vapour and cigarette smoke on an...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

ENT in this issue...The Future of ENT (Mar/Apr19)

Chris CoulsonENT Surgeon; Managing Director of endoscope-i E: chris@endoscope-i.com The future, predict it at your peril’, said me – just now. But despite this (rather late) warning, we have managed to commission five articles from futurists within our midst. The...

Cochlear implant – should we follow the curve?

Slimmer electrodes were developed by cochlear implant companies under the premise of hearing preservation (HP). Electrode types included stylet-curved electrodes sheath-curved electrodes, and straight-flexible electrodes. Previous reviews did not compare sheath and straight electrodes. A systematic review and meta-analysis were...

What we need to know about the new frontier of inner ear therapies

This is an interesting and topical review of the emerging biotechnology and pharmaceutical solutions for hearing loss and related conditions such as tinnitus. This paper suggests we are on the cusp of a very large step-change in the way we...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

What’s new in the cochlea?

Prof Furness in this article rounds up the steps and leaps being made by the scientific community to develop therapies to support, rejuvenate and / or replace the cochlear structures. David’s electron microscope images of the cochlear structures are world...

Assessment of genetic disorders: congenital sensorineural hearing loss

Severe or profound sensorineural hearing impairment (SNHI) is a common birth defect, affecting approximately 1 in 1000 newborns [1]. SNHI may result from environmental causes or have a genetic basis. The genetic causes can be further subdivided into non-syndromic (isolated...

9th Beijing International Audiology Conference

The 9th Beijing International Audiology Conference, organised by the Beijing Society of Audiology, was successfully held at the China National Convention Center. Nearly 1000 distinguished audiology experts and industry specialists from both China and overseas gathered for this significant occasion.

3rd International Symposium on Inner Ear Therapeutics

L’Institut de l’Audition (Centre Pasteur, Paris) and the International Society for Inner Ear Therapeutics (ISIET), with de collaboration with ENT-HNS Moroccan Collège (CEMORL), are organising the 3rd International Symposium on Inner Ear Therapeutics entitled ‘Inner Ear Therapeutics: Updates and Challenges...

Local dexamethasone infiltration in tonsillectomy

Intravenous dexamethasone is routinely given during tonsillectomy for its effects on postoperative pain and nausea. This Chinese randomised study divided 240 children undergoing tonsillectomy into three groups, receiving either no steroid, intravenous dexamethasone, or the same amount of dexamethasone infiltrated...

Will it ever happen?

Audiology is a rapidly evolving field, with many exciting developments on the horizon. David Baguley identified some topics of interest, and asked some international experts ‘will it ever happen?’ Gene therapy for deafness After years of development, gene therapy for...