You searched for "genetic"
The pioneer of precision: Wolfgang Steiner and the evolution of transoral laser surgery
It is rare that a single clinician entirely changes the course of the management of a particular condition. Steiner was one such clinician. Wolfgang Steiner was to transoral laser microsurgery what Grandmaster Flash was to hip-hop or James Brown was...Systemic agents in thyroid cancer
For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...Wilde and the foundations of medical epidemiology
William Wilde (father of Oscar) was renowned as an otologist, but less well known for his work in epidemiology. The bedrock of the modern discipline of public health is good data collection, and we hear from our good friend, Ray...Can we prevent chronic rhinosinusitis?
The old adage ‘prevention is better than cure’ is considered by Professor Hopkins in respect to chronic rhinosinusitis, a condition affecting around 10% of the adult population and associated with huge impact on quality of life and economic cost. A...
Pediatric Ear Diseases: Diagnostic Imaging Atlas and Case Reports
This book has been painstakingly compiled to produce a detailed atlas of high resolution CT images of the paediatric temporal bone. The five chapters over 160 pages and 242 high quality figures are very well structured and thoughtfully laid out....
Surgery of vestibular schwannomas with peritumoral oedema
This is an interesting retrospective study evaluating peritumoral oedema on magnetic resonance images and correlating it with the intra-operative tumour characteristics and outcome. The study results found that vestibular schwannomas with peritumoral oedema were associated with greater incidence of hypervascularity...
Role of the insula and orbitofrontal cortex in tinnitus related distress
It is estimated that 5% of the population suffer from chronic tinnitus with 17% of those suffering emotional distress. The authors attempted to study the neural correlates of tinnitus-related distress using functional magnetic resonance imaging (fMRI) during an Emotional Stroop...
Implantable devices and large magnets – do they mix well?
Although all brands are MRI safe at 1.5 T, the active middle ear implant system Vibrant Soundbridge (VSB), is special since it houses two magnets. These include a magnetic floating mass transducer (FMT) and an audioprocessor fixing receiver magnet which...
BAHA stability measurement in children
This useful paper reports the experience of using resonance frequency analysis for single stage bone-conduction implants in a paediatric population. A smartpegTM is attached to the abutment and vibrated by a close quarters magnetic field. The amount of vibration is...
Algorithm for malignant otitis externa
Timely detection and effective management of this potentially fatal condition cannot be overemphasised. This study presents 16 cases over 12 months in a tertiary referral centre. Most patients had diabetes and others were immunocompromised due to radiotherapy, immunosuppressive medication or...
Reliability of Koos classification
Vestibular schwannoma (VS) tumour size has been considered the primary determinant of hearing outcomes and facial nerve function according to several published studies. Varying methods are used to estimate the size and volume of the VS with very little consensus...
