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Adenoid cystic carcinoma – insights from a national database

Adenoid cystic carcinoma (AdCC) is a rare cancer of the salivary glands that accounts for approximately 1% of all head and neck malignancies. Hallmarks of this cancer type include a predilection for perineural infiltration, a prolonged clinical course with late...

Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

The hidden enemy of microtia reconstruction: cholesteatoma

Although ear reconstruction for concha-type microtia is generally successful, its frequent association with congenital aural stenosis introduces a hidden risk of cholesteatoma due to disruption of epithelial migration. This negatively affects hearing and reconstructive outcomes. This single-centre retrospective case series...

Surgical challenges in advanced or recurrent thyroid malignancy

The management of thyroid malignancy and extent of surgery is controversial, especially considering the limitations of preoperative diagnosis. Neil Tolley provides guidance and reminds us of our responsibility not to over-treat. In the UK, 16% of thyroidectomies are performed for...

Multidisciplinary airway simulation workshops: ‘preparing your team for the difficult airway’

Can human factor issues be better addressed within a multidisciplinary learning environment? Would this improve team working and patient outcomes? Are these important training considerations? Mona Thornton discusses the experience of a multidisciplinary simulation airway workshop in the unit she...

Paediatric hearing following chemotherapy

This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...

Open hearing-aid fittings or closed

There is always a balance between different types of hearing aids and their advantages and disadvantages that influence choice of device and ultimately user preference. Personal choice also plays a role when deciding on behind the ear or in ear...

Hearing preservation and device benefit following implantation of short or hybrid electrodes

Hybrid or short electrodes have increasingly been used in the literature in order to combine electrical with hearing-aid stimulation. However, hearing preservation of the residual low-frequencies are of utmost importance in this attempt. The present study compared hearing preservation and...

Military acoustic trauma: incidence and management

This is a retrospective study on the effects of acute acoustic trauma on the hearing thresholds of 225 military personnel. The main symptom after acute acoustic trauma due to firearm use was tinnitus. The authors consider it as the main...

Paediatric pain control post-tonsillectomy

The use of codeine in the paediatric population is widely debated since the American Food and Drug Administration (FDA) published warnings regarding overdose and death following the usage of codeine. Codeine is metabolised by the polymorphic cytochrome PY4502D6 (CYP2D6) in...

A cost reducing protocol for magnetic resonance imaging in patients suspected to have acoustic neuroma

Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have an acoustic neuroma. However, inappropriate referrals for imaging are not helpful, especially with the growing need to reduce costs. In this study the authors compared two audit...

Possible correlation of ABR changes with prognosis in sudden sensorineural hearing loss

A sensorineural hearing loss (SNHL) of 30dB or more affecting at least three frequencies and occurring over less than three days is classified as ‘sudden’ SNHL (SSNHL). Treatment is urgently undertaken with systemic and/or intra-tympanic steroids, and ijn some cases...