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Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Sham controlled trial: BPPV

I was drawn to this study and it proved an enlightening read; it also is a good example of where recommendations of a Cochrane review for long-term evidence of benefit have been acted upon! The study looked at the efficiency...

One airway, one disease - not for everyone!

While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...

Don’t be too apologetic: disclosing communication difficulties

People who stutter are frequently considered less intelligent or less confident, and are often discriminated against. These negative perceptions have been found to differ slightly across different cultural groups. For Hebrew speakers in Israel, having a stutter can have a...

A more comprehensive management for eosinophilic chronic rhinosinusitis after FESS

In recent years there has been increasing recognition of eosinophilic chronic rhinosinusitis which, in particular, results in persistent symptoms and recurrence of nasal polyps, even after FESS surgery. It therefore calls for measures adjuvant to FESS to stop persistence of...

Still not smelling

Post-Covid anosmia/hyposmia is a troublesome persistent symptom for lots of patients. Management is still elusive. This was a nationwide survey of ENT practitioners. Of the 715 surveyed members, only 7.4% responded. Most performed a nasal endoscopy, 60% ordered an MRI...

Maxillomandibular advancement and airway morphology

This is a cadaveric study comparing alterations in airway volume. Seven advancements of the maxillomandibular complex were undertaken, each with a 2 mm incremental advancement being scanned with a total of eight scans per cadaver. They showed that comparisons between...

Should we leave a reconstructed auricle exposed?

Microtia results in psychological and functional morbidity and total auricle reconstruction offers the affected individual a more cosmetically pleasing ear. The art of dressing postoperatively can be heterogenous between surgeons. This single-centre retrospective study based in China compared complication rate...

In the United States, do people with dysphagia have a higher chance of being dysphonic?

Dysphagia and dysphonia can co-occur due to their shared anatomy and physiology. Previous studies have considered this relationship and determined that certain conditions, such as cancer, laryngeal impairments or neurological disorders, may lead to problems with both swallowing and voice....

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

In conversation with Dr Helen Bevan: Approaching change in the NHS with a new mindset

Dr Helen Bevan has been a leader of large scale change in the English National Health Service (NHS) for more than 20 years and was recently recognised as one of the 60 most influential people in the history of the...

Early Egyptian medicine: nasal trauma and surgery in the Edwin Smith Papyrus

In ancient Egypt, with its towering pyramids and bustling cityscapes along the Nile, there existed a deep-rooted civilisation that excelled in more than the grandeur of monumental architecture. Frequent wars and battles shaped Egyptian society, not only defining its political...