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Passive smoking and rhinosinusitis
One would expect that subjects exposed to more passive smoke would have a significantly increased level of rhinosinusitis. This study looked at a reasonable number of sinusitis and control subjects (404 and 165) using hair nicotine as an assessment of...
Chronic rhinosinusitis, are we treating the same disease?
Chronic rhinosinusitis (CRS) is a heterogenic disease. The effects of heterogeneity on treatment outcome are not very clear. Authors used clinical features such as endoscopic findings scores and full blood count findings in addition to analysis of 35 molecular markers....
Delirium post-op
This is a retrospective study from Japan analysing 102 patients who underwent oral cancer resection and free flap reconstruction. Postoperative delirium occurred in a third of these patients. An increased risk was identified in those with high preoperative albumin, postoperative...
Work and the risk and carcinoma of the larynx
This is a census on the national cancer registry in France to detect professions at a higher risk of squamous cell carcinoma of the larynx. During the period 2001-2016 there were 244 registered cases of cancer of the larynx. Amongst...
Clinical pathological features associated with malignant change in oral leukoplakias
This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...Laryngology: past, present and future
Two laryngological authorities trace the history of laryngology, from ancient Rome to the modern day. The structure of the vocal folds was a matter of conjecture until the renaissance when anatomists such as Andreas Vesalius and Julius Casserius demonstrated the...The Airway Intervention Registry: Recurrent Respiratory Papillomatosis (AIR: RRP) data collection
Laryngeal papillomatosis remains a frustratingly difficult condition to treat. Adam Donne and Steven Powell tells us about a collaborative project aiming to enhance patient care. The first UK Recurrent Respiratory Papillomatosis registry opened in April 2018 through the AIR (Airway...The changing spectrum of cancer of the oropharynx: dilemmas and future directions
The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....A funny thing happened whilst your boss was away at a conference
What is the difference between God and Professor Sir Donald Harrison? God is everywhere – Sir Donald is everywhere except at the Royal National Throat Nose and Ear Hospital! This was a common joke about Sir Donald, who was much...Fifteen years of vestibular implant research in humans
Implants: it’s all in the balance! Prof Guyot and his team give us an update on their research in addressing bilateral vestibular deficits via an implant. Doctors are often unaware that people, even young, may lose vestibular function on both...
Multiple surgeries for RRP – does a greater number of operations result in a worse voice outcome?
Recurrent respiratory papillomatosis (RRP) of the larynx remains a challenging condition to treat, with a number of affected patients requiring multiple operations to remove recurrent disease over the course of their lifetime. At the most severe end of the spectrum,...
