Clinical pathological features associated with malignant change in oral leukoplakias

This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...

A histological test for LPR?

Laryngopharyngeal reflux (LPR) is often considered to be a contributory factor to the development of a spectrum of laryngeal abnormalities including vocal cord leukoplakia and dysplasia. This is especially the case when traditional risk factors, such as tobacco smoking, are...

Management of oral white patches with malignant potential

This paper focuses on a rare but aggressive form of leukoplakia with malignant potential and is an important reminder of the need for specialist management to those in allied specialties such as ENT that may initially be referred these oral...

Proliferative Verrucous Leukoplakia; which one is this one?

Oral leukoplakia has the potential for malignant change and it may frequently require histological analysis and a period of regular clinical observation. The majority of oral leukoplakia remains constant but there is a subset that progress to carcinoma. The authors...