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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Royal Society of Medicine – the year ahead

Professor Peter Andrews and Professor Manohar Bance look forward to 2022-23.

Cochlear Implant Patient Assessment: Evaluation of Candidacy, Performance, and Outcomes – Second Edition

The second edition of Cochlear Implant Patient Assessment aims to become a point of reference for all professionals involved in assessing cochlear implant candidacy and interested in broadening their knowledge to maximise the hearing capabilities of their patients. This book...

Biologics for deafness

Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....

Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C

Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...

3rd UK Smell & Taste Symposium

Following the success of events in 2022 and 2023, Professor Carl Philpott, Professor of Rhinology and Olfactology at the University of East Anglia, and Duncan Boak, CEO of Fifth Sense, the charity for people affected by smell and taste disorder,...

Audiology in this issue...Genomics

Priya Carling, AuD, Director and Consultant Audiologist, Kent Hearing Ltd, UK. E: priya@Kenthearing.com As a working clinical audiologist, my focus every day is predominantly diagnostics of hearing loss, closely followed by management of ear pathology and rehabilitation of hearing loss...

The 66th Hallpike Symposium - BAAP

The 66th Hallpike Symposium took place on the 15th November 2024. It was organised by Drs Carolyn Ainsworth and Rosa Crunkhorn, Audiovestibular Medicine (AVM) Consultants at Guy’s and St Thomas’ NHS Foundation Trust, London. The theme of the event was ‘Recognising systemic conditions associated with audiovestibular dysfunction for the practicing clinician’.

8th Baltic ENT Congress

Austėja Kučinskienė, senior resident. Attending the Baltic Otorhinolaryngology Congress held great personal significance for me. Organised by the Lithuanian Society of Otorhinolaryngology every three years under the esteemed leadership of President Professor Eugenijus Lesinskas, it took place in Vilnius, Lithuania,...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

4th Annual Inner Ear Disorders Therapeutics Summit

Terrri Gaskell, Chief Technology Officer, Rinri TherapueticsHeld in Boston, USA, this was an essential gathering that captured the growing excitement in both the biotech and clinical communities surrounding the rapid advancements in hearing loss therapies. With the potential to significantly...

Vestibular functions of hereditary hearing loss patients with GJB2 mutations

Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...