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Tinnitus treatment device from concept to commercialisation

Innovation in the field of healthcare is fraught with nearly insurmountable challenges. Bringing a novel product to the market requires a new (patentable) idea that can be reduced to practice, manufactured at scale, and can pass all regulatory barriers. In...

Validating a new international cholesteatoma classification – a necessary but challenging task

A European and Japanese joint consensus statement was published in 2017 which proposed a new cholesteatoma staging classification (EJS), with four stages. This follow-up publication aims to assess the internal and external validity of the staging system using existing prospectively...

Biologics for deafness

Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....

Tinnitus and music

Marc Fagelson discusses how not just hearing loss, but tinnitus and hyperacusis and impairments to an individual’s ability to process music can adversely affect one’s quality of life, as well as their overall interactions from a societal and personal perspective....

Falls and ASL users

A mixed-method pilot study was carried out to assess the cognitive load of sign language among users and, consequently, the possible risk of injurious falls. The study specifically investigated the possible risk of falls due to the simultaneous activity of...

Assessment of the incidence of LPR in the Greek population using the Reflux Symptom Index

Using the self-administered nine-item Belafsky Reflux Symptom Index (RSI) questionnaire, the authors of this article assessed the prevalence of laryngopharyngeal reflux (LPR) in the general adult Greek population as well as predisposing and associated factors for developing LPR. They found...

Patients with advanced oral cavity carcinoma are not candidates for the ‘organ preservation’ approach

The authors of this study, from the University of Michigan, evaluated the role of induction chemotherapy for patients with stages III and IV resectable oral squamous cell carcinoma. Nineteen patients were initially enrolled in the induction chemotherapy cohort. Patients with...

Passive smoking and rhinosinusitis

One would expect that subjects exposed to more passive smoke would have a significantly increased level of rhinosinusitis. This study looked at a reasonable number of sinusitis and control subjects (404 and 165) using hair nicotine as an assessment of...

Chronic rhinosinusitis, are we treating the same disease?

Chronic rhinosinusitis (CRS) is a heterogenic disease. The effects of heterogeneity on treatment outcome are not very clear. Authors used clinical features such as endoscopic findings scores and full blood count findings in addition to analysis of 35 molecular markers....

Delirium post-op

This is a retrospective study from Japan analysing 102 patients who underwent oral cancer resection and free flap reconstruction. Postoperative delirium occurred in a third of these patients. An increased risk was identified in those with high preoperative albumin, postoperative...

Work and the risk and carcinoma of the larynx

This is a census on the national cancer registry in France to detect professions at a higher risk of squamous cell carcinoma of the larynx. During the period 2001-2016 there were 244 registered cases of cancer of the larynx. Amongst...

Clinical pathological features associated with malignant change in oral leukoplakias

This is a retrospective study from Sweden where 234 patients, diagnosed between 2003 and 2013 with a median nine-year follow-up, were reviewed. Of these 234 patients, 11.5% developed oral squamous cell carcinoma. Non-homogenous leukoplakia showed a 15-times higher transformation rate...