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Hearing loss and Alport syndrome

Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...

Dizziness in OSA patients– is there a link and can CPAP treat it?

This is a small study which proposes an interesting hypothesis - that in patients with both dizziness and OSA, treatment of their sleep disorder can provide resolution of their dizziness symptoms, which were otherwise refractory to standard treatment, particularly in...

Cognitive function is preserved in episodic vestibular disorders

Cognitive deficit in bilateral vestibular failure in particular, but also in unilateral vestibular failure, is well documented. The authors designed this prospective study to determine if deficits in cognition, as well as anxiety and depression, were present in episodic vestibular...

European funding for the tinnitus research network TINNET

Over 70 million people in Europe experience tinnitus, and for seven million it creates a debilitating condition. Severe tinnitus is often associated with depression, anxiety and insomnia, resulting in an enormous socio-economic impact [1]. It has been estimated that 13...

Military noise induced hearing loss and the Lost Voices report: the evolution of earshot

Brigadier Robin Garnett gives us a snapshot of the 2014 Royal British Legion report on hearing problems of Service personnel and veterans. The difficulties in assessing and managing hearing loss are reiterated in this article, with an introduction to how...

Hearing aid outcomes in older adults: what and when to measure

What matters to older adults when purchasing a hearing aid? Larry Humes explores the domains that should be measured for this key group. This article identifies key domains of hearing aid outcome in older adults. Increasingly, third-party payers and private-pay...

Have we reached our limits in endoscopic skull base surgery?

As being an anterior skull base surgeon becomes the aspiration of many ENT trainees, Professor Nicolai gives his personal insights into the future for this exciting subspeciality. Having been directly involved in the evolution of transnasal endscopic surgery (TES) since...

Targeted focal parathyroidectomy

Leanne Hamilton and Louise Clark describe their technique for helping to localise parathyoid adenomas. Surgically this can be difficult, so careful preoperative evaluation using imaging as described can help minimise difficulties intraoperatively when identifying the parathyroid adenoma. Preoperative imaging has...

Old age is hard to swallow

This article takes us through the diagnosis and management of swallowing problems common in older age. As our global population continues to grow and live longer, dysphagia will continue to be a global problem which needs to be recognised, understood...

Neurological idiopathic disease: a shared journey for NASA and medicine

Whilst Southampton can’t really be described as an extreme environment, experiments carried out in the city have certainly been taken out of this world. Robert Marchbanks discusses one of the associations between Southampton, The International Space Station and tympanic membrane...

Medialisation laryngoplasty can relieve pain related to voice use

Odynophonia, or pain associated with voice use, is a relatively uncommon manifestation of glottal insufficiency related to vocal fold motion impairment (VFMI). Its incidence is approximately 15% in patients with vocal fold paresis. Medialisation laryngoplasty (ML) was popularised by Isshiki...

Rhinoplasty: state-of-the-art

Rhinoplasty surgery has evolved over the years, and Pietro Palma introduces a further new concept. When flicking through the topics of major rhinoplasty meetings, the astute observer will realise that, at present, there are two mainstream schools of rhinoplasty, which...