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The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

An effective treatment for post Covid-19 smell loss?

It is well understood that calcium levels in the nasal mucous affect the ability to smell, with higher levels having a negative impact, and some studies have shown increased calcium levels in patients suffering with Covid-19-related olfactory dysfunction. Calcium chelating...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

Less Than Full time Training in Otolaryngology

A recent Statement from the Association of Surgeons in Training (ASIT) stated that in 2011 there were 17 otolaryngology trainees in Less Than Full Time training (LTFT) [1]. Otolaryngologists in LTFT posts (17/151) is the largest group after general surgery...

Redeployment of audiologists during COVID-19

As the demand on intensive therapy units in the NHS increased, volunteers from the audiology profession stepped in to support colleagues. Here, they share their experiences of caring on the frontline. Redefining normal: from outpatients to the ICU By Emilee...

Medical and surgical management of performing vocalists

Dr Steven Zeitels is widely recognised as the foremost laryngologist of his generation. He has been at the forefront of innovation for 25 years, and has treated innumerable high-profile singers, most recently Sam Smith and Adele. Here, he gives us...

Medical training initiative (MTI): stepping outside the box

Medical training initiative (MTI) scheme in the UK are becoming increasingly available and are actively supported by ENT UK. Despite this, knowledge of them is limited and there can be a mismatch between supervisors and potential candidates. Our authors, Manuela...

Chronic rhinosinusitis update

There is still a lack of awareness of chronic rhinosinusitis (CRS) despite its burden, calling for events such as the recent Global Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Awareness Day. Research findings from recent publications by Backaert et al have...

Team based learning in speech language pathology graduate courses

According to the author of this article, the role of a speech language pathologist involves clinical problem solving in both diagnostic and treatment processes. Problem solving involves cooperative collaboration with clients and their parents. Therefore, in this pilot study, the...

Endoscopic airway interventions in children

Open surgery for paediatric airway pathologies such as subglottic stenosis was hailed as revolutionary when many of today’s paediatric ORL specialists were in training. Equipment, facilities and training has moved on and the high-quality optics in modern endoscopes, coupled with...

Hearing conservation in military operations

Navy audiologists protect service members’ hearing, ensuring situational awareness, safety and mission readiness in noisy military operations. Active-duty navy audiologists are naval officers who apply their specialised skill sets and serve as subject matter experts in hearing conservation and communication...

Monstrous craws and horrid butchery: a concise history of thyroid surgery

Prior to the foundation of our speciality, thyroid surgery had a dubious reputation and universally dismal outcomes. Jenny Walton casts a critical eye over this dark chapter. Diseases of the thyroid gland have been referenced in historic texts for well...