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Preoperative risk factors: when do you need to refer to the haematologist?
It is essential that clinicians are able to identify and assess which patients are in the high risk category for bleeding during ENT surgery. A full history, including medications, herbal remedies taken, any other medical co-morbidities and family history of...
Investigation of the role of KPNA2 biomarker in oral SCC invasiveness
This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...
DVT prophylaxis in cranial procedures
Deep vein thrombosis (DVT) is a result of disturbed balances in blood flow patterns, blood clotting factors promoting coagulation and vessel wall endothelial injury. The subsequent disruption of coagulation and fibrinolysis mechanisms lead to venous clot formation and propagation. The...
The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...When dinosaurs ruled the earth
Optimism is abundant in medical research, but frequently ends up being tempered with reality. In his inimitable style, Chris Potter looks back over his career – starting with his medical school memories of Bentley-driving ENT consultants, and moving forward through...
Understanding cough
The prevalence of chronic cough in the adult population is 10–12%. Chronic cough is common and costly, and represents a substantial clinical and economic burden. Duration-based classification guides evaluation. Distinguishing acute (<3 weeks), subacute (3–8 weeks), and chronic (>8 weeks)...Microneedles enable inner ear precision medicine
Developing safe, reliable and efficient ways to deliver therapeutics into the cochlea is a key challenge. In this article, the authors share their work to develop microneedles to address this challenge. The era of precision medicine of the inner ear...
Cholesteatoma and Ear Surgery
The book Cholesteatoma and Ear Surgery is a selection of papers and presentations, including round tables and symposia, that constitute the proceedings of the 10th International Conference on Cholesteatoma and Ear surgery, a highly successful meeting that attracted over 1000...
