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Allergy – what’s in a name?

Allergy is defined as an “abnormal immune reaction to an ordinarily harmless substance” [1], however the meaning of the word has taken many forms since its introduction in 1906 by Austrian Paediatrician and Immunologist, Clemens von Pirquet [2]. Combining his...

OBITUARY: Bernard Colman (1924-2020)

Bernard Colman at his leaving party at the old Radcliffe infirmary in 1989, which was his retirement year. Born above a corner shop in Wolverhampton on 17 October 1924, Bernard Colman entered Wolverhampton Grammar School in 1933 but left early...

Chronic rhinosinusitis management: back to the future?

Immunology is a dim and distant medical school memory to many ENT surgeons, but the increasingly complex immunology of chronic rhinosinusitis is fascinating (honestly!). Medical management options in CRS no longer just involves saline and steroids, and we need to...

Giacomo Puccini’s laryngeal cancer

Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...

Audiological monitoring in ototoxicity - Are we doing enough?

In this article Ghada Al-Malky explores the dichotomy of life-saving, yet hearing loss-causing medication, and questions whether the hearing healthcare community is doing enough to prevent preventable hearing loss. Ototoxicity is the damage to hearing and / or balance functions...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

Fifth Sense James Lind Alliance Priority Setting Partnership for smell and taste disorders

Research priorities in the past have been dominated by the quixotic curiosity of individual academics and the capricious generosity of funding organisations. There must be a better way... At Fifth Sense, research is fundamental to the work we do. Above...

Emerging robotic systems for head and neck surgery

As of December 2020, seven robotic surgical systems have received approval for use in different jurisdictions, and many more task-specific robots are in the pipeline. Jack Faulkner takes us through what’s on the horizon for head and neck cancer surgery....

The European TINNET COST Action BM1306

Winfried Schlee describes how a major European funding award is bringing together experts who are committed to collectively developing a better understanding of tinnitus. This work is vital if we are to pioneer effective treatments for the condition in its...

Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

In conversation with Helen and De Wet in Paris: cochlear implants in the year 2074

The World Congress of Audiology (WCA), held in Paris, France, in September 2024, provided a fantastic opportunity to reconnect with colleagues from around the globe. I took the chance to sit outside in the sunshine with De Wet Swanepoel from...