You searched for "ELS"

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Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Do nasal septal deviation and septoplasy affect Eustachian tube function?

The authors suggest that nasal septal deviation (NSD) or septoplasty possibly affect Eustachian tube (ET) function. They conclude this from their prospective study on 25 patients who underwent septoplasty for NSD. These patients aged above 14 years had no other...

Which surgical procedure is more effective in treating OSA? Tonsillectomy or modified uvulopalatopharyngoplasty?

Obstructive sleep apnoea (OSA) is a recognised condition that is increasing in prevalence, affecting the quality of life in certain individuals. Although the first line management is non-surgical, this paper highlights the two different surgical procedures offered to patients. The...

Eustachian tube dysfunction usually improves following endoscopic sinus surgery

This study investigated effects of endoscopic sinus surgery (ESS) on eustachian tube dysfunction (ETD) and factors associated with improvement. This was a retrospective study which included 302 patients over 17 years old who underwent ESS between 1 December 2016 and...

Cystic fibrosis – sinus surgery delays chronic Gram-negative lung infection

This prospective clinical follow-up study is of 106 patients with cystic fibrosis in Copenhagen. Morbidity and mortality in CF are significantly associated with pulmonary colonisation and infection, usually with Gram-negative bacteria. Initially this can be well treated with antibiotics until...

Staying safe during endoscopic ear surgery

There is growing interest in using rigid endoscopes rather than traditional operative microscopes to perform transcanal middle ear surgery. Rigid endoscopy provides a high resolution, wide-angle view of the tympanic cavity through minimally invasive surgical portals. In this article, Elliott...

A novel graft material for endoscopic tympanoplasty using the pre-tragal SMAS layer

The traditional biological graft materials for providing a scaffold for tympanic membrane reconstruction include temporalis fascia as well as conchal and tragal perichondrium/cartilage. This group from Taiwan present a novel graft option using the superficial musculo-aponeurotic system (SMAS) layer. They...

SONNET 3 – the next generation in hearing technology for ultimate user experiences

MED-EL has announced the new SONNET 3, its smallest and lightest behind-the-ear audio processor for cochlear implant users. Integrating cutting-edge technology to enhance hearing experiences, it is designed to deliver an exceptional hearing performance alongside the latest connectivity features -...

In conversation with Frederik Dikkers

Declan Costello, editor of ENT & Audiology News, has recently enjoyed a couple of conversations with Professor Emeritus Frederik Dikkers that you can now watch on YouTube.

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Recording of electrode voltages (REVS) to determine extra-cochlear electrodes

Determining whether electrodes are sitting within the cochlea can be difficult as the checks run by the programming software cannot always determine this. In some cases, patients may be unable to give the audiologist detailed feedback which can complicate the...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...