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Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

Audiological monitoring in ototoxicity - Are we doing enough?

In this article Ghada Al-Malky explores the dichotomy of life-saving, yet hearing loss-causing medication, and questions whether the hearing healthcare community is doing enough to prevent preventable hearing loss. Ototoxicity is the damage to hearing and / or balance functions...

ERS 2025

Michaella Cameron, ST6 (OOPE), North Thames Deanery, United Kingdom The 30th ERS Congress welcomed 1,850 participants from around the world to a warm and collegial environment – perfect for newcomers like myself. Set in the vibrant city of Budapest, the...

BACO 2015: Meet the Key Brits

The triennial BACO is always a feast of academic and social activity – and BACO 2015 promises to be as busy as ever. We hear from three of the key British speakers who are making big contributions to this year’s...

Facing up to the challenge of behavioural observation in infant hearing assessment

The ability to assess detection and discrimination of speech by infants has proved elusive. Dr Iain Jackson and colleagues discuss how new technologies and fresh approaches might offer valuable insight into young infants’ behavioural responses to sound. The limits of...

Experience on the front line

21st January 2021 Back to basics Yesterday I went right back to where my medical career began. I grew up in Germany, bilingual. A prerequisite to studying medicine in Germany is that applicants have to spend two months working as...

Mastoid surgery for cholesteatoma

Landmark Paper: Toner JG, Smyth GDL. Surgical Treatment of Cholesteatoma: a comparison of three techniques. Am J Otol 1990;11(4):247-9. Canal wall up or canal wall down? Chris Aldren discusses the landmark paper that attempted to provide a definitive answer for...

Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour

Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

The ups and downs of overseas research – the inner ear at altitude

Conducting research at extreme altitude presents unique challenges. This study of the inner ear at 5350m navigates setbacks in a quest for scientific discovery. Having completed a diploma in mountain medicine in my foundation years, I decided to undertake a...

Professor Heinz Stammberger’s pioneering contribution and legacy in the field of FESS

It is no exaggeration to say that functional endoscopic sinus surgery would not exist in its current form without Heinz Stammberger. Prof Valerie Lund traces the development of this relatively recent surgical technique. In the early 1980s, a happy combination...