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Head and neck cancer and PET-CT
Positron emission tomography-computed tomography (PET-CT) is an imaging technique in which abnormalities of tissue metabolism are precisely superimposed onto the anatomy. It relies on the premise that malignant cells are more metabolically active compared with non-malignant cells. On this basis,...
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
New MRI technique assesses treatment response in skull base osteomyelitis
This paper describes another useful imaging technique to monitor Necrotising Otitis Externa (NOE). Echoplanar diffusion weighted magnetic resonance (DW MR) shows high signal on the ‘ADC map’ with active disease and this reduces in signal intensity as symptoms improve. This...
Clinicopathological features of follicular variant of papillary thyroid carcinoma
The follicular variant (FV) of papillary thyroid carcinoma (PTC) is characterised by the presence of nuclear features of PTC together with a follicular growth pattern. It is currently reported to make up 11.8% to 53.3% of all PTC cases. It...Measuring audiological outcomes in the paediatric setting
In this article Marlene Bagatto argues that a range of outcome measures and instruments need to be implemented when working with children and families. She demonstartes how these support both clinicians and families. The primary goal of early hearing detection...Standards for Safe Listening – how they align and how some differ
The ‘Make Listening Safe workgroup’ is an initiative of The World Health Organization (WHO) in the framework of the World Hearing Forum and is committed to creating a world where nobody’s hearing is put in danger due to unsafe listening....How will our grandchildren view COVID-19?
Alan Johnson, known to our readers as the former President of ENT UK, gives us his thoughts on the COVID pandemic, looking at it through the lens of other health crises. As I write, COVID-19 is displacing almost all other...
Olfactory and gustatory recovery in coronavirus patients after six months
It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...
The role of cVEMPs in the diagnosis of Meniere’s disease
This study sets out to determine the most useful metrics to use from cervical-vestibular evoked myogenic potential (c-VEMP) tests when the diagnosis of Meniere’s disease (MD) is unclear, or as a follow-up tool. It is known that cVEMPs can detect...
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
Sinonasal undifferentiated carcinoma – slowly getting there
The rarest of the rare, sinonasal tumours form only a small part of the total number of head and neck tumours and undifferentiated carcinoma (SNUC) is one of the rarest of this group. There is some data (and some expert...
