You searched for "neural"

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Stem cells in nasal polyposis

Chronic rhinosinusitis with nasal polyps (CRSwNP) is common and is multifactorial with increased T-helper 2 response and active role of interleukin 5. It can be associated with asthma and control of CRSwNP improves lower airway disease. Due to constant cellular...

Childhood speech processing in background noise

Normal childhood development of the auditory systems involves mapping sounds to meaning and the neural coding of speech. Children are often subjected to adverse listening environments such as high levels of background noise. This paper aimed to delineate the effects...

CRSwNP and smell – is it just the obstruction?

Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...

Peripheral nerve stimulation for chronic refractory pain

Peripheral nerve stimulation (PNS) plays an important role in treating chronic refractory pain syndromes that manifest in limited distributions and overlap with areas of neurologic innervation. The process is generally thought to capitalise on the inhibition and activation of pain-related...

X-ray vs. intraoperative testing for determining cochlear implant placement

Most cochlear implant centres confirm electrode position after surgery using X-rays to ensure optimal electrode placement. As well as transorbital view X-rays, this team check placement using impedance measures and neural response telemetry (NRT) performed intraoperatively. The former indicates whether...

Advances in auditory implants

This article provides an overview of auditory implants. Implanted auditory devices may be classified into bone conduction implants (BCI) and active middle ear implants (AMEI) that stimulate cochlear hair cells, and cochlear implants (CI) that stimulate neural structures. CIs bypass...

How rare is vocal fold paralysis after spinal and epidural anaesthesia – should we be more concerned?

The authors present an unusual case of right vocal fold paralysis. Their patient was a 38-year-old woman who experienced new onset dysphonia following neuraxial anaesthesia (NA) for a caesarean section. Flexible nasendoscopy showed a right VFP with fixation in the...

Microgravity: an extreme environment for otolith organs

Motion sickness in a car can be upsetting for all involved. Transferring this concept into a tiny cabin bound for space could have devastating consequences. Are the processes involved in ‘space motion sickness’ the same as motion sickness? How do...

Update on the development of an implantable vestibular prosthesis

Cochlear implants have revolutionised the management of profound hearing loss. Might vestibular implants be the future for the treatment of bilateral vestibular failure? James Johnston and Neil Donnelly explore. The vestibular system is highly complex, integrating visual, labyrinthine and proprioceptive...

Hidden hearing loss in humans

Awareness of cochlear synaptopathy (‘hidden hearing loss’) is growing. Chris Plack gives us an introduction to the condition, defining it and reviewing recent research in humans and animals with respect to noise exposure. The main cause of hearing loss is...

The tip in rhinoplasty

Getting the tip right (both its position and its shape) is vital in rhinoplasty. George Marcells eloquently gives us his perspective on how to get it right. “Many surgeons overly concentrate on the profile at the expense of the frontal...

Balance and vestibular disorders in children

Discover the world of paediatric vestibular assessment and management from the team at Alder Hey Children’s Hospital, which is revolutionising services in this field. Dizziness and balance problems generate significant morbidity in children of all age groups. Vestibular disorders are...