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Biofilms in Otitis

If you haven’t already heard of biofilms, this book will tell you that they are multicellular networks of bacteria encased in a matrix, a complex multidimensional biologic fortress that protects bacteria against changes in the environment, host immune responses and...

Medical control of allergic rhinitis in children

The authors of this randomised trial aim to answer an important question – which is better: daily versus on demand use of intranasal steroids (fluticasone probionate) or antihistamines (levocetirizine dihydrochloride) for symptomatic control of allergic rhinoconjunctivitis secondary to pollen? The...

Salt in surgical simulation

Cheap, easily accessible and realistic methods of reproducing surgery through simulation are the ideal. Here a group from Tokyo, Japan report on a method of producing 3D printed skulls and mandibles to use for simulated surgery. A high resolution CT...

Bright young things: executive functioning in younger, older and aphasic people

Executive function comprises several higher order cognitive processes such as planning, organisation, adaptation, maintenance, monitoring and decision making. It is thought that difficulties in cognitive flexibility in people with aphasia are associated with difficulties in executive function rather than the...

Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody

Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...