You searched for "trial"
Intratympanic treatments for subjective idiopathic tinnitus
Direct application of medication into the ear is long established, going back as far as written records. In the modern era, greater understanding of aural anatomy revealed that drugs instilled in the middle ear could potentially diffuse into the cochlea...
Vestibular paroxysmia, diagnostic controversy clarified?
Historically, the cause of vestibular paroxysmia (VP) had been attributed to neurovascular compression of the eighth cranial despite the observation that such compression is very common in asymptomatic subjects. This paper, part of International Classification of Vestibular Disorders (ICVD) by...
Reflux, a pre-disposing factor in paediatric OME?
It is almost 20 years since the Lancet publication by Tasker et al describing gastric juice in the glue ear of children. This paper attempts to look at the body of literature which has focused specifically on the clinical association...
Extrapolating lessons from vestibular schwannoma management
This paper presents a delightfully simple and sensible hypothesis for the management of benign schwannomas in the head and neck region. They have taken the approach used for the management of vestibular schwannomas and used the same principles to assess...What has NAIROS taught us about septoplasty?
Septoplasty is a commonly performed procedure worldwide for nasal obstruction associated with a deviated nasal septum. In the UK, with long waiting lists for septoplasty, there is a large and unexplained variation in the incidence of this procedure between individual...
Patients with severe uncontrolled CRSwNP respond to biologics in the real world
Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...The integration of targeted therapy and surgery in advanced thyroid cancer clinical trials
One of the headline speakers, Mark Zafereo, will be talking at IFOS about thyroid cancer. We hear from his team about some of the areas they will be discussing. Locally advanced thyroid cancer generally refers to patients who have significant...Neuromod closes €10 million financing to accelerate commercialisation
Neuromod, an Irish medical device company specialising in tinnitus, has closed a €10 million equity financing deal in a Series B fundraising expansion to expand the availability of tinnitus treatment device, Lenire. Financing was oversubscribed and led by existing investors...
IV dexamethasone versus LA infiltration during paediatric tonsillectomy
Postoperative nausea and vomiting following tonsillectomy is important to control for improved oral intake and satisfaction following surgery. Optimal management is still debated. This team from Beirut conducted a randomised double blind clinical trial comparing the effect of intravenous dexamethasone...The effects of polypharmacy in the elderly
Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...
Peripheral nerve stimulation for chronic refractory pain
Peripheral nerve stimulation (PNS) plays an important role in treating chronic refractory pain syndromes that manifest in limited distributions and overlap with areas of neurologic innervation. The process is generally thought to capitalise on the inhibition and activation of pain-related...
