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Pharyngocutaneous fistula after total laryngectomy
Pharyngocutaneous fistula (PCF) after total laryngectomy is a serious complication post-surgery, and can lead to prolonged hospitalisation, adding delays in postoperative chemoradiotherapy. This Turkish retrospective study looked at 166 patients who underwent total laryngectomy for laryngeal cancer, although it is...
Role of ultrasonography-guided fine-needle aspiration in management of the neck after chemoradiotherapy
Primary chemoradiotherapy (CRT) is a well-established treatment for locally advanced head and neck squamous cell carcinoma (HNSCC). However, not every patient has a complete response to this treatment modality, necessitating eventual salvage neck dissection. Some patients with persistent adenopathy following...
Bile acids and pharyngeal malignancy
Laryngopharyngeal reflux is a commonly described condition. There is strong evidence linking gastro-oesophageal reflux with oesophageal carcinomas. Gastric refluxate consists of gastric acid, pepsin and bile acids. The roles of pepsin and acidic conditions in the development of laryngopharyngeal carcinoma...
Paediatric hearing following chemotherapy
This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...
Are elective facelifts a good idea after head and neck cancer radiotherapy?
The aim of this study was to assess the safety of elective cervicofacial rhytidectomy following radiotherapy for head and neck squamous cell carcinomas (HNSCC). A greater proportion of HNSCC patients are infected with certain strains of the human papillomavirus, which...
Tricky post-laryngectomy swallows
Despite improvements in chemoradiation therapy and the adoption of organ preservation for some head and neck cancers, total laryngectomy remains the treatment often providing best survival chances for advanced laryngeal cancer. This article reviews the causes of dysphagia post-laryngectomy and...
Total lower lip reconstruction: a review
Total or near total defects of the lower lip may result from trauma, cancer ablation or congenital causes. Defects usually involve the full thickness and include skin, muscle and mucosa. There are a number of techniques for the one stage...
Thyroid nodule update
This excellent article summarises the current diagnostic difficulties with an endocrine gland that frequently produces nodules, some of which may harbour malignancy. At 50 years of age and over there is about a 50% chance of having a nodule; at...
Sinonasal undifferentiated carcinoma – slowly getting there
The rarest of the rare, sinonasal tumours form only a small part of the total number of head and neck tumours and undifferentiated carcinoma (SNUC) is one of the rarest of this group. There is some data (and some expert...
Narrow band imaging improves diagnosis of malignant laryngeal lesions
The manufacturers of narrow band imaging (NBI) claim better visualisation of mucosal abnormalities when compared with simple white light. The primary aim of the study was to compare the diagnostic accuracy of NBI and white light to diagnose malignant laryngeal...
Does use of pectoralis muscle myocutaneous flap (PMMCF) reduce postoperative pharyngocutaneous fistula complication after salvage laryngectomy?
Salvage laryngectomy for recurrent laryngeal carcinoma following failed radiotherapy or chemoradiotherapy is associated with high postoperative complication rate. The primary aim of this paper was to assess whether use of muscle myocutaneous flap (PMMCF) as an interposition graft reduces the...
