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Going beyond patient care: discovering alternative roles in audiology
In this article we hear about Husmita Ratanjee-Vanmali’s journey from clinical practice to implementing global strategies for clinical practice, education, and innovation across South Africa, Canada and Denmark. In the constantly evolving dynamic global sector, have you ever considered what...Tele-audiometry – a ShoeBOX solution
Access to hearing assessment is a global challenge. In relation to the global burden of hearing loss World Health Organisation’s (WHO’s) recent estimate (2013) is that 360 million people in the world have disabling hearing impairment. Two-thirds of these people...Physician health and wellness amidst a global pandemic
Dr Westerberg attended a workshop on Physician Wellness hosted by Dr Osler a few years ago at our Canadian Society of Otolaryngology-Head and Neck Surgery meeting. The list of symptoms of stress and burnout resonated as typical of almost a...Hearing loss and Alport syndrome
Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...Medical training initiative (MTI): stepping outside the box
Medical training initiative (MTI) scheme in the UK are becoming increasingly available and are actively supported by ENT UK. Despite this, knowledge of them is limited and there can be a mismatch between supervisors and potential candidates. Our authors, Manuela...The Graham Fraser Foundation
Graham Fraser (1936-94) was a pioneering otolaryngologist, in whose memory the Graham Fraser Foundation was set up, and an eponymous annual lecture and a travelling fellowship in otology were established. It’s an honour to profile the Foundation in this extended...
Cystic fibrosis – sinus surgery delays chronic Gram-negative lung infection
This prospective clinical follow-up study is of 106 patients with cystic fibrosis in Copenhagen. Morbidity and mortality in CF are significantly associated with pulmonary colonisation and infection, usually with Gram-negative bacteria. Initially this can be well treated with antibiotics until...
Fungal rhinosinusitis
Allergic fungal rhinosinusitis (AFRS) has been defined by the following characteristics: presence of nasal discharge, nasal obstruction, decreased sense of smell or facial pressure for 12 weeks, mucin within the sinus cavity containing fungal hyphae and degranulating eosinophils, endoscopic evidence...
The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...
Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...
Performing ethnic aesthetic rhinoplasty
This article reviews principles of performing rhinoplasty in non-Caucasian patients, exploring patient expectations based on differences in race, ethnicity and culture. One of the main challenges is a lack of well-established ideal facial measurements for different non-Caucasian groups. The authors...
