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Eosinophilic complications during dupilumab therapy

Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...

3D planning of soft-to-hard tissue ratios in orthognathic surgery

This multinational systematic review examined publications over a six-year period up to December 2023, focusing on orthognathic surgery. It follows an earlier review by the same group, which had reported low validity in the use of 3D software for soft-to-hard...

The ‘umbrella furling’ deflation technique for cuffed tracheostomy tube - a useful tip for an easier tracheostomy insertion

In this article, the authors describe a quick and effective technique to assist with the maximal deflation of a tracheostomy tube cuff prior to insertion, thus making the process easier with less chance of damage to the cuff and a...

COVID-19: UCT-Africa Virtual ENT transcends academic silos

The COVID-19 pandemic has been a global catastrophe with far-reaching consequences felt across many fronts around the world. One such aspect is the training of the future generation of ENT surgeons. With routine elective activity curtailed, academic conferences cancelled, and...

Rehabilitation of single-sided deafness with cochlear implants

The relatively recent emergence of cochlear implantation as a potential means of restoring hearing to a deafened ear, in the presence of normal hearing in the other ear, has proved an exciting and yet surprising development. James Tysome explores the...

In conversation with Professor Eugene Myers: My life in ENT

In a series of interviews, former Chairman of the Editorial Board for ENT & audiology news, Professor Patrick J Bradley, speaks with eminent otolaryngologists who have retired (or are about to retire) from practice. Our first is with Professor Gene...

Follicle stimulating hormone receptors; an aid for the pathologist?

It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...

Can laryngeal sensitivity testing predict aspiration and pneumonia in dysphagic patients?

The laryngeal adductor reflex (LAR) is characterised by brief vocal cord closure in response to laryngeal stimulation. It is important in swallowing physiology as it represents a mechanism for airway protection. The authors of this study examined whether the absence...

What characterises dysphagia in unilateral vocal fold impairment?

The closure of the vocal folds during swallowing is known to contribute to airway protection along with epiglottic inversion and closure of the false vocal folds. It is therefore plausible to expect that unilateral vocal fold impairment without complete closure...

Older patients hospitalised for pneumonia: what factors determine survival after discharge?

A high proportion of older adults hospitalised for pneumonia may have co-existing risk of aspiration due to dysphagia. The authors of this single-centre retrospective cohort study followed up patients over the age of 65 who were admitted to hospital with...

Unanswered questions in adult ototoxicity associated with platinum-based chemotherapy

Do the potential side-effects on hearing and tinnitus need to be a ‘necessary evil’ of platinum-based chemotherapy? How strong is our evidence base when offering advice to patients and fellow clinicians? David Baguley and his team from the University of...

A day with Peter Prinsley MP

Our former editor, Ray Clarke, spent a day at Westminster with Peter Prinsley, an ENT surgeon turned Member of Parliament. Peter Prinsley had recently retired from more than 40 years as an NHS Consultant ENT surgeon in Norfolk when he...