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CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

Novel wax solvent

This paper describes an open label, prospective study undertaken by the authors to demonstrate the safety and efficacy of a novel topical wax solvent. This new product has a dual action using a bicarbonate system to disrupt the esters and...

A conservative approach to treat ameloblastoma

Ameloblastoma is an odontogenic tumour that is benign but locally aggressive and is associated with local recurrence. They are rare, accounting for 1% of oral tumours, and occur almost exclusively in the jaws. It is more common in the mandible...

Understanding osseointegration for the otologist

Bone conduction implants are hearing devices that require osseointegration to create a stable and reliable interface between the hearing device and the skull to deliver sound to the cochlea. This article reviews the physiology of osseointegration, factors that may lead...

Predicting outcomes in rhinology using fluid dynamic models

This article discusses the rhinological applications of computational fluid dynamics (CFD) – a method derived from engineering applications, such as aerodynamics. Its appeal is that it can provide simulated data on airflow velocity, pressure, resistance, temperature, humidity, heat flux and...