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The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Allergen specific subcutaneous immunotherapy helps in prolonged control of allergic rhinitis

One of the commonest allergens involved in perennial allergic rhinitis is house dust mite. A good proportion of these cases prove intractable to treatment with oral and intranasal antihistamines and intranasal steroid sprays. Immunotherapy is considered a useful alternative and...

The stubborn polyp cases are ‘different’

The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...

Extended benefits of cochlear implantation in the elderly

With the challenges presented by an ageing population, Louise Craddock and Charlie Huins describe the benefits of cochlear implants for deaf elderly adults that go beyond improvement of hearing and speech understanding. Introduction People aged over 65 make up 7.4%...

Children like to talk

When a health professional, including speech and language therapists, treats a child, they will often ask the parent or relative of the child for information on the issue and its impact. Yet children will frequently have an opinion on their...

Inflammation associated with presbyacusis

Inflammaging and presbyacusis is a topic that few audiologists consider in their daily clinical routine due to lack of training in this area. Inflammaging is a chronic state of inflammation present throughout the body. The classic 1965 work by Rosen...

Tinnitus in patients on therapy with PPI and in PPI non–users

Tinnitus is a chronic and debilitating condition and approximately 10% of the population is afflicted. A myriad of pharmacological treatments for tinnitus are available but only a few controlled studies have shown positive results. The relationship between proton pump inhibitors...

In conversation with Professor Janet Wilson

As she approaches her retirement from clinical practice, Professor Janet Wilson speaks to our Editor (and fellow laryngologist) Declan Costello about surgical training, research, diversity, literature and the future. You have had an immensely successful career in ENT – how...

The ear, nose and throat anaesthesia practice of Dr John Snow (1813-58)

News of the first successful public demonstration of general anaesthesia in Boston, Massachusetts in October 1846 reached Britain in mid-December of that year. James Robinson, a London dentist, gave the first anaesthetic in the United Kingdom when, on 19 December,...

The role of YO-IFOS in enhancing collaboration between young physicians in Europe

Young ENT surgeons realise the importance of international collaboration – we hear about a group that was formed just 18 months ago. During the meeting of the International Federation of Otorhinolaryngological Societies (IFOS) in 2017 in Paris, a group for...

Awareness raised on World Hearing Day 2024

The 2024 World Hearing Day on 3 March provided 39 grants to WHD to support activities in 22 countries as part of its small grants programme.

The initial management of nasal trauma

Fractures of the nose are the most common facial fractures and reported to be the third most common fracture of the human skeleton. Nasal trauma can lead to obvious or more subtle loss of function or form and cosmetic compromise....