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Interleukins, cilia and polyps
Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...
Infection in prosthetic temporomandibular joints
This is an overview from an internationally recognised TMJ surgeon. It is a comprehensive article highlighting the incidence is likely to be underestimated and prevention the main objective. Eradication is very difficult. Not surprisingly, a lot of the conclusions are...INTEGRATE: Uniting collaborative research in ENT
Exposure to clinical research as a trainee is often sporadic and unstructured, despite it featuring in both the GMC’s Good Medical Practice and the ISCP’s syllabus for all surgical specialities, including otolaryngology [1,2]. The majority of trainees undertake small-scale research...
Does transoral robotic surgery improve outcomes among patients with head and neck cancer of unknown primary?
A tonsillectomy and tongue base mucosectomy is becoming increasingly accepted as the optimal surgical intervention to aid in identifying the primary source of a p16+ / HPV-related squamous cell carcinoma (SCC) of unknown origin, given that this disease almost exclusively...
Person-centred care, enhancing audiology student understanding across the globe
Over 200 students registered for a multinational virtual event facilitated by the Ida Institute. The aim was to determine levels of student understanding and approaches to person-centred care (PCC), alongside the opportunity to evaluate the benefits of this approach to...
Voice outcomes following extended laser resections for laryngeal cancer
It is now widely accepted that the oncological and voice outcomes following transoral laser microsurgery for early T1a glottic cancers are equivalent to, if not superior to, traditional radiotherapy. Voice outcomes following more extensive resections have not been as frequently...
Augmented reality – a quick overview of potential technology
Is that the optic nerve? Where is the carotid? Both questions you would prefer to know the answer to upfront. This article discusses if augmented reality can help us with surgical navigation around the skull base. Although endoscopic skull base...Chocolates for laryngectomees
When The Chocolate Line in Bruges, Belgium, was approached by the charity, Shout at Cancer, there was always going to be something very special and innovative in the pipeline! Shout at Cancer’s Thomas Moors has been chatting with Julius Persoone,...
Predictors of complications in patients undergoing oral cavity cancer surgery
Surgical management of oral cavity cancers is complex, frequently involving extensive resections and complicated reconstructions. Quantification of risk in an individual patient may allow surgeons to more effectively identify patients at higher risk of complications and develop strategies for prevention,...
Intraoperative MRI use during pituitary tumour resection
This article provides an overview of intraoperative MRI (iMRI) use in transphenoidal surgery (TSS) for pituitary tumours. Traditionally imaging of the surgical field during surgery involves intraoperative fluoroscopic imaging or neuronavigation which help to avoid injury to critical structures but...Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...
