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Rare, aggressive pituitary adenomas
This is a review article on published cases of the rare Crooke’s pituitary adenoma. These tumors are usually invasive and may be clinically aggressive; they may be endocrinologically silent or may produce adrenocorticotropic hormone causing Cushing’s disease. They often recur...COOL therapy for cisplatin-induced hearing loss
Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...Hidden hearing loss in humans
Awareness of cochlear synaptopathy (‘hidden hearing loss’) is growing. Chris Plack gives us an introduction to the condition, defining it and reviewing recent research in humans and animals with respect to noise exposure. The main cause of hearing loss is...
Preoperative CT checklist (using the ‘CLOSE’ mnemonic) improves identification of anatomical variants for endoscopic sinus surgery
Computed tomography (CT) scans of the paranasal sinuses act as roadmaps for endoscopic sinus surgery (ESS) and careful inspection preoperatively warns the operating surgeon of critical anatomical variants. This study aimed to investigate if implementation of a pre-ESS CT checklist...
Damage to the cochlear nucleus with electrocautery to the cochlear nerve
This study is of importance to neurotologists and neurosurgeons. It is unclear why patients with NF2 have poorer outcomes with an auditory brainstem implant compared to non-tumour patients. This effect is postulated to be due to damage to certain cells...
Platelet-rich plasma to reduce post-tonsillectomy haemorrhage and pain
Minimising haemorrhage and promoting healing of raw areas are cornerstones for uneventful and speedy recovery after tonsillectomy. In this single-blinded prospective experimental study, application of platelet-rich plasma to one side tonsillar bed has been compared to the other side in...10th Winter Meeting on Otology
By Prof Onur Çelik, MD, Sc, Department of Otolaryngology, Manisa Celal Bayar University, Turkey. The 10th Winter Meeting on Otology was held virtually on 13 February 2021. The main context of the meeting was ‘hearing in extreme conditions’. More than...
SCC of pinna – which histological features could predict prognosis?
Cutaneous squamous cell carcinoma (SCC) of the pinna is reported to have a higher rate of metastasis than cutaneous SCC originating from elsewhere - up to 16% compared with less than 2% for the latter. The authors aimed to assess...Central auditory changes in SNHL
Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...
The search for the holy grail of rhinosinusitis: another step towards phenotyping in CRS wNP?
For many years, scientists and clinicians have been trying to understand the infinite variability within the term ‘rhinosinusitis’ using radiology, basic science, epidemiology and then using their insights to solve the riddle of management: how to explain why some patients...
Biologics for deafness
Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....
