You searched for "depression"

1204 results found

Predicting the need for salvage laryngectomy

The treatment of laryngeal cancer has seen a shift towards organ preservation strategies with non-surgical treatment offering equivalent survival outcomes. Nonetheless, salvage total laryngectomy (SLT) remains an important curative management option in cases of treatment failure or recurrence. The authors...

Scoring system to predict hearing impairment following hemifacial spasm surgical treatment

The authors analysed brain stem auditory evoked potentials prospectively in 100 patients undergoing endoscopic microvascular decompression for management of hemifacial spasm over a period of two years. They then developed a scoring system based on electrophysiological events to predict the...

Is combined two wall decompression approach a better surgical outcome for Grave’s orbitopathy?

This retrospective study looked at the outcome of endoscopic medial wall combined with transcutaneous lateral orbital wall decompression in Graves’ orbitopathy. The following parameters were studied: reduction in proptosis; change in visual acuity and diplopia. A total of 36 orbits...

Anatomic guidelines to endolymphatic sac in transmastoid approach – a cadaveric study

This study involved cadaveric dissection using transmastoid approach in cadaveric embalmed five half heads and posterior fossa approach in fourteen. The sac was identified by electron microscopy. The relatively consistent measurements were the relationship of the operculum to the internal...

A conservative approach to treat ameloblastoma

Ameloblastoma is an odontogenic tumour that is benign but locally aggressive and is associated with local recurrence. They are rare, accounting for 1% of oral tumours, and occur almost exclusively in the jaws. It is more common in the mandible...

By the people, for the people: a multidisciplinary facial nerve clinic with a difference

Facial nerve palsy is regularly seen in ENT clinics. Underlying diagnoses are excluded, and the patient is often then discharged to ‘see how it goes’, with or without an ophthalmology referral. Here, Catherine Meller describes how she and her team...

Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease

Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...

Acoustic schwannoma regression post-Gamma Knife treatment

In this retrospective study the authors studied the optimal interval following radiosurgery for differentiating between true growth of tumour versus pseudoprogression using serial volumetric data. A total of 118 patients with a median tumour volume of 0.74cm3 at Gamma Knife...

IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Follicle stimulating hormone receptors; an aid for the pathologist?

It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...

Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

One airway, one disease - not for everyone!

While 85% of asthmatic patients have rhinitis, only 20-30% with rhinitis have asthma. Together with atopic dermatitis (AD), rhinitis and asthma form a triad that tend to co-exist in patients (multimorbidity). This co-existence raises the possibility of genetic mechanism. Authors...