You searched for "ototoxic"

150 results found

COOL therapy for cisplatin-induced hearing loss

Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...

Polypharmacy in the vestibular clinic

Polypharmacy is defined as the simultaneous use of five or more medications and its prevalence is increasing. Dizziness or vertigo are common side effects of polypharmacy. Despite advancements in patient data management, there remains limited information on polypharmacy in patients...

Simulation and otologic surgery

Ensuring adequate exposure and developing surgical skills for trainees has been an ongoing challenge. In this article, the authors reviewed the role of simulation and its role in developing skills in otologic surgery for trainees. Virtual-reality (VR) simulation models have...

Impact of delaying otologic surgery

In this Belgian study, the authors looked at the impact of delaying otologic surgery by sending an online survey to 44 adult patients diagnosed with benign ear pathology whose surgery was postponed due to the COVID-19 pandemic. The questionnaire was...

Hearing Conservation: In Occupational, Recreational, Educational, and Home Settings (1st edition)

Hearing Conservation was released in September 2011 by Vishakha Rawool, Professor of Audiology at West Virginia University. The book is intended for audiologists, researchers and graduate level students, as well as other professionals working in the fields of hearing conservation...

Cobalt hip implants and auditory-vestibular outcome

Cobalt-chromium (Co-Cr), metal-to-metal hip implants were commonly used until several side-effects were reported due to an increased level of Co and Cr metal ions in patients’ blood. Although this type of hip replacement was almost completely abandoned, there are still...

Are we screening enough? Genetics in adult-onset sensorineural hearing loss

Sensorineural hearing loss (SNHL) in adults can be a result of multiple factors such as age, noise exposure and autoimmune pathology. In a group of patients, no cause is identified and the SNHL is treated as idiopathic. Authors evaluate the...

What are the risk factors for new onset tinnitus?

Factors associated with tinnitus have mainly been studied cross-sectionally. Tinnitus is associated with hearing loss, noise exposure, ototoxic medication, head and neck trauma, smoking and depression and anxiety. Only a few studies exist that report on risk factors for developing...

Newborn sensorineural hearing loss – what is the incidence?

In the last two decades, the introduction of newborn screening for hearing loss has dramatically lowered the average age of newborn hearing loss diagnosis to around two to three months of age. The benefits of early diagnosis are manifold, enabling...

Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Intracranial complications of otitis media – the difference between kids and adults

Despite a decrease in intracranial complications from otogenic infections since the introduction of antibiotics, there is still morbidity and mortality associated with this. This group from the Netherlands conducted a retrospective review of all the patients treated for intracranial complications...

What’s new in the cochlea?

Prof Furness in this article rounds up the steps and leaps being made by the scientific community to develop therapies to support, rejuvenate and / or replace the cochlear structures. David’s electron microscope images of the cochlear structures are world...