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Aural fullness in Ménière’s disease
This survey of the Finnish Ménière’s Association aimed to examine the severity and consequences of aural fullness, the least reported cardinal symptom of Ménière’s disease. An initial pilot survey informed a second, restructured survey, giving a total of 726 respondents...
What is the right balance to strike in the management of anaplastic thyroid cancer?
This is a pragmatic article on a difficult and much debated subject. Management of anaplastic thyroid cancer (ATC) can feel like making decisions between a rock and a hard place, and this article suggests one path to help navigate some...Hearing loss and Alport syndrome
Alport syndrome (AS) includes a group of hereditary diseases caused by mutations in the COL4A3, COL4A4 or COL4A5 genes. These genes are responsible for the biosynthesis of α3, α4 and α5 collagen IV chains, which are located in the glomerular...Recalcitrant chronic rhinosinusitis: What to do next?
Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...
Vitamin C, a possible remedy for seasickness?
The internet is full of devices and medicines vying for superiority over which one is the best for preventing seasickness. This study was based on the following observations: elevated histamine levels trigger seasickness; blockade on histidine decarboxylase prevents seasickness while...
Persistent imbalance after traumatic brain injury is central in origin
Several residual symptoms, including dizziness and imbalance, can follow traumatic brain injury, no matter how mild. This study focused on the mechanisms, peripheral and central, underlying the complaint of persistent imbalance in patients with chronic mild traumatic brain injury (mTBI)....
Chronic phase of concussion and stability of gaze
It has been known that vestibular symptoms can persist for several months after concussion. The authors designed this study to assess the effect of chronic concussion (more than one year) on gaze stability and the relationship between deficits in gaze...
Neuro-Ophthalmology and Neuro-Otology: A Case-Based Guide for Clinicians and Scientists
As Daniel Gold points out in his preface, the idea for this title was borne from the observation that, despite the considerable overlap between the fields of neuro-ophthalmology and vestibular neurology, there is no single text that marries these two...Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease
Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...
Time to endoscopic sinus surgery and outcomes
A well written prospective study, which demonstrates that patients who require endoscopic sinus surgery, should be operated on without long delay since this achieves better and more sustained outcomes. There were 1493 patients undergoing primary nasal surgery who had completed...
Role of maxillary sinus irrigation as an adjuvant to current management of chronic rhinusitis without polyposis
Several decades have passed since irrigation of maxillary sinuses generally became a treatment of the past. A more recent concept of biofilms may have evoked new interest in this past procedure, fraught with its own issues. In this study, the...
