Journal Reviews
Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
The polyp shrinker
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
Reasons for attending annual hearing aid review appointments
The aim of this study was to investigate what factors influence hearing aid users’ decision to attend or not attend an annual hearing aid review (HAR) appointment. Two separate surveys were created for attendees and non-attendees. An invitation letter was...
A safe and useful surgical procedure for allergic rhinitis?
Although the best management of allergic rhinitis is medical, intractable cases are not uncommon. Immunotherapy helps but is more practical if there is a single allergen involved. The authors compare the effects of submucosal inferior turbinoplasty alone with submucosal turbinoplasty...
TIVA in FESS: a meta-analysis
This meta-analysis is from Rochester, New York, and aims to add more evidence for the use of TIVA in endoscopic sinus surgery (FESS) to arm rhinologists keen for a quick, bloodless FESS in the discussion with anaesthetists who prefer inhalation....
Allergic rhinitis, the usual suspects
Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...
Smell training is also effective in older patients
Olfactory loss is a common problem with a significant impact on quality of life. It has been demonstrated that olfactory training (OT) improves olfactory function in younger patients, but this study focuses in on patients aged 45 years and older....
An alternative view and access point
Fungal sinusitis is a common problem and it is well recognised that it can be difficult to remove all of the fungal matter from the maxillary sinus to ensure no recurrence or residual disease. This study describes a technique utilising...
Rhinotillexomania - how bad can nose picking get?
This is a fascinating first case report of rhinotillexomania associated with empty nose syndrome (ENS). Rhinotillexomania encompasses compulsive, pathological nose picking and is a variant of self-harm. Tranchito and Chhabra describe an elderly patient presenting with longstanding symptoms of nasal...
Closure of septal perforations
This Belgian retrospective observational study looked at the success rate and predictive factors for success when bilateral advancement flaps were used via an external approach. In total, 111 patients were included in the study over a 16-year period. The mean...
Inverted papilloma
This Croatian study aimed to look at risk factors associated with malignant transformation and recurrence in 91 cases in a single institution over a 20-year period. There were 66 men and 25 women included in the study. The authors reported...
Patient factors associated with spontaneous CSF leak
This article highlights the role of obesity, sleep apnoea and raised intracranial pressure as linked pathologies in the aetiology of the spontaneous cerebrospinal fluid (sCSF) leak. The authors link sCSF leak with obesity and comment on sCSF leak incidence increasing...
