Journal Reviews
Globus, reflux or perhaps both?
We rarely do an ENT clinic without encountering a patient with persistent or recurring feeling of a lump or foreign body in the throat. We are also familiar with patients dreading to hear the C word after the endoscopic examination...
Adult Rhinosinusitis Clinical Practice Guideline update
This is a summary of the ‘Clinical Practice Guideline: Adult Sinusitis’ from the American Academy of Otolaryngology-Head and Neck Surgery Foundation. This is an update of the 2015 version. Evidenc-based statements: 1a. Differential diagnosis of acute rhinosinusitis: Clinicians should distinguish...
Eosinophilic complications during dupilumab therapy
Dupilumab is a humanised monoclonal antibody that targets type 2 inflammation by blocking IL-4 and IL-13 signalling. Reported adverse events from its use include injection site erythema, conjunctivitis, arthralgia and hypereosinophilia. The potential for more severe eosinophilic-related complications such as...
Not the answer yet, but it may be in the future
AI is certainly a topical issue these days and radiomics refers to techniques which allow the extraction of quantitative features from medical imaging to produce large data sets for clinical problem solving. This paper looks at CT imaging of the...
Budesonide nasal irrigation for chronic rhinosinusitis: is it effective and safe?
Budesonide respules used in nasal irrigations as part of chronic rhinosinusitis management are usually at a dose of 0.25 mg to 2 mg, which is substantially higher compared to budesonide nasal spray, typically ranging from 64 to 256 micrograms. Hence,...
Posterior nasal neurectomy – long-term data shows tailing off of benefits but still improvement after three years
It is well understood that allergic rhinitis has a very detrimental effect on quality of life for afflicted patients. This study looks at patients with allergic rhinitis but no other associated sinonasal or respiratory diagnoses. Patients with a history of...
Congenitally anosmic patients do have fewer olfactory foramina
It has been previously established that patients with Kallman’s syndrome (very much associated with anosmia) have a similar number of cribriform plate foramina when compared to controls. As non-invasive CT assessment of the cribriform plate is now possible in cadavers,...
Saddle nose deformity repair – structured approach
We often come across saddle noses in our specialist rhinology clinics. The saddle nose deformity represents collapse of the cartilaginous and / or bony nasal support structures resulting in dorsal height loss. Acquired cases are due to trauma or surgery...
Temperature-controlled radiofrequency treatment of the nasal valve confers sustained benefit
Aiming to investigate long-term efficacy and safety (three years post treatment), this was an extension of a previous multicentre, prospective, single-blinded, randomised controlled trial that investigated the effectiveness and safety of temperature-controlled radiofrequency treatment (TCRF) to the nasal valve (NV)...
Patients with severe uncontrolled CRSwNP respond to biologics in the real world
Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...
Do intranasal corticosteroids resolve eustachian tube dysfunction?
Eustachian tube dysfunction is a widely prevalent problem, both in children and adults. In many ways, it affects the quality of life in terms of earaches, feeling of blockage and variable hearing. Use of intranasal corticosteroids is customary but whether...
Chronic rhinosinusitis update
There is still a lack of awareness of chronic rhinosinusitis (CRS) despite its burden, calling for events such as the recent Global Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) Awareness Day. Research findings from recent publications by Backaert et al have...
