Journal Reviews

Clinical histopathology of 250 parotidectomy patients

30 April 2020 | | Head and Neck | OMFS, fine needle aspiration cytology (FNAC), oral and maxillofacial surgery, parotid gland tumour, parotidectomy, salivary gland

Clinical histopathology of 250 parotidectomy patients This is a retrospective study of 250 consecutive parotidectomy patients at units in Belgium and the Netherlands. The sensitivity and specificity of FNAC was 64% and 99% respectively, the sensitivity being slightly lower than...

Using evidence and international consensus to guide treatment of thyroid nodules

1 October 2018 | | Head and Neck | fine-needle aspiration (FNA) biopsy, imaging features, thyroid nodule, ultrasound, well differentiated thyroid carcinoma

The authors of this practical review paper highlight a growing issue within thyroid surgery, where high-quality ultrasound has increased the detection of subclinical nodules: what do we do with the patient presenting with an ‘incidental’ thyroid nodule? This has both...

Risk of malignancy in non-diagnostic thyroid FNACs

1 March 2017 | | FNA, diagnostic, thyroid cancer, thyroid nodule

Thyroid nodules are present in between 21-68% of the general population. The evaluation of these nodules to exclude thyroid carcinoma includes fine-needle aspiration cytology (FNAC) and a non-diagnostic cytology result occurs between 8-20% of the time. This retrospective cohort study...

Expanding the role of FNA in thyroid nodule decision-making

1 November 2016 | | BRAF, cytology, fine-needle aspiration (FNA), papillary thyroid cancer, preoperative diagnosis

Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...