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2880 results found

OTO-104 in noise-induced and cisplatin-induced hearing loss

These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...

Charles Skinner Hallpike and the Hallpike Prize

The British Association of Audiovestibular Physicians introduced the Hallpike Prize in 2009 as an award to stimulate the pursuit of knowledge in relation to the field of audiovestibular medicine. Julian Ahmed celebrates the history of the great man the award...

Swallowing outcomes following partial laryngectomy: objective assessment and pre-operative predictive factors

Partial laryngectomy constitutes one of the treatments for early stage glottic carcinoma (i.e. T1N0 and T2N0) in specialised centres. Over the years, several partial laryngectomy and reconstruction techniques have been described in the literature. The choice of technique depends on...

Adolescence, drug use and body image

Teenagers are notoriously conscious of how they are perceived by others. Dr Saraiva and colleagues explain how this can lead to problems with substance abuse for both boys and girls, and discuss the different substances they may encounter. Adolescence is...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...

The effect on taste buds due to severing of the chorda tympani nerve

The long-term histological effect on taste buds following cutting of the chorda tympani in humans is not clear. Confocal laser scanning allows in-vivo examination of the same group of taste buds and is aiding our understanding of why patients recover...

Tongue tie – just a snip?

This article regarding ankyloglossia raises an eyebrow; surely it’s just a snip isn’t it? Seemingly not. The authors describe two types of tongue tie – the first being posterior, with the frenulum being short and tight, the second being anterior,...

Transnasal endoscopic orbital decompression

Surgery for the eye complications of Grave’s disease is an area that, over the years, ENT has become more and more involved in due to our ability to access the orbit endoscopically. In this article, the authors describe their technique...

HPV and ENT; should we vaccinate boys?

David Black and Charlie Hall reiterate Vin Paleri’s pleas for a common sense evidence-based approach by those who allocate healthcare resources to the now urgent issue of HPV-related disease. They discuss the merits of different vaccines and the need for...

Innovations in remote/teleaudiology patient care

Audiometry remains the gold standard in hearing evaluations. Changes in the delivery of audiometry remain a key challenge in providing a telehealth approach to hearing care. The team at Lyon University Hospital validated an innovative approach to solving this challenge,...

AM and the neck

Infections with atypical mycobacteria (AM) are increasing, especially with the decline in BCG immunisation. The most frequent presentation is a lymphadenopathy in an immunocompetent child. This poses a difficult diagnostic challenge if the clinician is not aware of this entity....

Vestibular functions of hereditary hearing loss patients with GJB2 mutations

Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...