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Biologics for deafness

Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....

Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C

Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...

Paediatric hearing following chemotherapy

This study examined the effect of platinum compounds on hearing in 104 children with solid tumours. As would be expected, this group was heterogeneous and included a range of ages, tumour types, chemotherapeutic agents and dosing regimens. Age-appropriate audiometry was...

ENT in this issue...Women in Leadership

Sujana S Chandrasekhar, MD, Past President, AAO-HNS/F; Secretary-Treasurer, American Otological Society; Consulting Editor, Otolaryngologic Clinics of North America; Recipient, AAO-HNS WIO Helen Krause Trailblazer Award and AMA Physician Mentor Recognition Award. Emma Stapleton Consultant Otolaryngologist, Cochlear Implant and Skull Base...

Exploring the role of oral microbiota in head and neck squamous cell carcinoma

Oral microbiota, especially Fusobacterium nucleatum, may improve survival and guide personalised treatment in head and neck squamous cell carcinoma. Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with a low five-year survival rate that has shown little...

Occupational dust exposure and nasal polyposis

This interesting European cross-sectional study demonstrates a link between occupational dust exposure and the presence of nasal polyposis. A random sample of textile workers (215) and retail store employees (101) in Portugal was taken, with clinical data gathered through a...

A comparison between artificial and cadaveric temporal bones in terms of providing realistic setting and structural details

Increasing difficulties, costs and risks of infection have led to the use of artificial temporal bones for training in mastoid and middle ear surgery. Whether these provide a realistic learning environment (face value) and offer structural details to learn from...

Vicarious (nasal) menstruation

Hippocrates himself is known to have said that when a woman’s menses are due, but instead of the usual vaginal menstrual flow, she has a haemorrhage from the nose, then this is a sure sign of pregnancy [1]. Artist’s impression...

Long-term outcomes of children and young people with cochlear implants

Introduction Profound childhood hearing loss has a huge impact on early communication skills, the acquisition of spoken language, and hence on educational attainments and employment prospects. Over the centuries, educators of the deaf attempted to overcome the challenge by using...

COVID-19: UCT-Africa Virtual ENT transcends academic silos

The COVID-19 pandemic has been a global catastrophe with far-reaching consequences felt across many fronts around the world. One such aspect is the training of the future generation of ENT surgeons. With routine elective activity curtailed, academic conferences cancelled, and...

4th Annual Inner Ear Disorders Therapeutics Summit

Terrri Gaskell, Chief Technology Officer, Rinri TherapueticsHeld in Boston, USA, this was an essential gathering that captured the growing excitement in both the biotech and clinical communities surrounding the rapid advancements in hearing loss therapies. With the potential to significantly...

5th Annual Inner Ear Disorders Therapeutics Summit

Coined by industry as the only meeting of its kind and uniquely positioned to share fresh ideas and assess viable approaches to your most pressing preclinical, translational, and clinical bottlenecks, the 5th Inner Ear Disorders Summit returns as a forum to benchmark learnings from past failures, reignite momentum and develop investment into the audiology therapeutic landscape.