You searched for "chemotherapy"

254 results found

Are there benefits of prophylactic swallowing exercises for patients with head and neck cancer?

This randomised controlled trial aimed to establish the impact of prophylactic swallowing exercises in patients undergoing chemoradiation therapy for head and neck cancer. The primary outcome was the functional oral intake scale (FOIS), although secondary measures for feeding tube use,...

Combination PPI and intralesional steroid treatment for recurrent laryngeal granuloma

The existence of a wide range of treatments for recurrent laryngeal granulomas (repeat surgery, high-dose proton pump inhibitor (PPIs), surgery with botulinum toxin injection, botulinum toxin injection alone, etc) is a testament to the refractory nature of this condition, with...

To montelukast or not to montelukast

Both histamine and cysteinyl leukotrienes play an important role in both seasonal allergic rhinoconjunctivitis (SARC) and asthma. A combination therapy against both was shown to give benefit both in vitro and in vivo. Authors wanted to test the efficacy of...

How to tackle the problem of ciprofloxacin-resistant ear infections?

The growing issue of ciprofloxacin-resistant ear organisms is certainly a pertinent one. The situation here in the UK, where ototoxic topical drops are frequently given initially in the presence of pus and a perforation, differs markedly from elsewhere where fluoroquinolones...

The nice therapist effect: does the therapeutic relationship matter?

Quality of relationships is considered a core component of all speech and language therapy work, yet there is little agreement of what constitutes a therapeutic relationship. This study describes a scoping review to map existing evidence that has investigated this...

Therapeutic alliance: more than the ‘nice person’ effect

Therapeutic relationship is considered a key component of many healthcare interventions, including speech and language therapy. Yet definitions and descriptions of what this concept comprises are ambiguous and sparse. This scoping review used the Joanna Briggs Institute guidelines to guide...

In conversation with Professor Paul J Donald

Prof Paul J Donald has recently stepped down as Chairman of the ORL-HN Department at UC Davis in Sacramento and is winding down to retirement. In this interview with Prof Pat Bradley, Prof Donald explains some of the highlights of...

Detecting cancer margins during robotic head and neck cancer surgery using ambient mass spectrometry

We have known about altered metabolism in cancer cells since Otto Warburg described it 97 years ago. But can we take advantage of this knowledge in curing cancer? Jim Higginson explains the value of smoke generated during cancer surgery. The...

Contemporary Transoral Surgery for Primary Head and Neck Surgery (Includes Companion Website) First Edition 2015.

This is a volume containing 16 chapters and indexed over 251 pages which covers the topic of transoral surgery (TOS) edited by Drs Hinni and Lott from the Mayo Clinic Arizona, Phoenix, USA. The chapters cover the topic of TOS...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

Speech predictors after glossectomy

This is a cross-sectional study from India where 69 patients were assessed for speech intelligibility and phonetics using an assessment tool in the local language. Volume defects were classified into thirds and the location of this defect noted. Not unsurprisingly,...