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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Drooling: what is it like to be unable to manage your own saliva?
Drooling in Parkinson’s is associated with less frequent and inefficient swallowing, resulting in a build-up of saliva in the mouth that then moves beyond the lips. It often causes discomfort as the skin becomes sore, and results in embarrassment. The...Optimising reflux diagnosis with Peptest
Patients presenting with persistent cough or hoarseness are often managed empirically, with treatments that address the symptoms, rather than the underlying cause. This can lead to prolonged diagnostic pathways, repeated follow-ups and patient frustration. Peptest offers a simple, non-invasive way...
Word-finding difficulties in Parkinson’s are as important as speech
Parkinson’s is typically considered to progressively affect speech and voice, with up to 89% of people with the diagnosis experiencing symptoms such as reduced articulatory coordination and a hoarse or breathy voice quality. Despite 80% of people with Parkinson’s experiencing...
MRONJ: surgical treatment outcomes and prognostic factors
This study from China assessed 197 patients with advanced mandibular disease who underwent radical surgery and had at least 6 months of follow-up. The extent of surgery varied from marginal resection and local flap closure, plate and pedicle flap to...Mentorship and its role in surgical training
Is there a principle which could help address multiple challenges in surgical training? One which has potential to improve recruitment and retention of staff to our specialty, quality of patient care and surgeon morale? Harry Spiers, an Academic Foundation Doctor...In conversation with Prof Peter John Wormald: The past, present and future of treating CRS
At ERS2023, Prof PJ Wormald will lecture on the past, present and future of treating chronic rhinosinusitis (CRS). We caught up with him recently to hear about the major improvements, the hypes and his dreams for the future of treating...
Remote consultations: bringing ENT in to the 21st century
The ongoing peaks and troughs of the COVID-19 pandemic have imposed unprecedented challenges on day-to-day healthcare provision that we all took as given across the globe prior to spring 2020! The pandemic has, in many ways, made us push boundaries...
